STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apaHBis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (281 aa)    
Predicted Functional Partners:
apaG
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri apag protein ApaG or b0050 or c0063 or z0059 or ecs0055 or sf0047 SWALL:APAG_ECOLI (SWALL:P05636) (125 aa) fasta scores: E(): 1.9e-38, 73.59% id in 125 aa.
  
  
 0.937
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.903
surA
Survival protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
 
 0.893
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
  
  
 0.836
ECA3425
Putative lipoprotein; Similar to Xanthomonas campestris ankyrin-like protein xcc4050 SWALL:Q8P3M1 (EMBL:AE012526) (325 aa) fasta scores: E(): 2.1e-08, 30.68% id in 264 aa, and to Serratia sp. MK1 accessory protein plaS SWALL:Q9X9D9 (EMBL:U37262) (251 aa) fasta scores: E(): 5.5e-07, 25.31% id in 237 aa. Also similar to ECA3424 (83.784% identity in 259 aa overlap).
 
 
 0.690
imp
Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
    0.667
ECA3424
Putative lipoprotein; Similar to Xanthomonas campestris ankyrin-like protein xcc4050 SWALL:Q8P3M1 (EMBL:AE012526) (325 aa) fasta scores: E(): 3.9e-08, 31.22% id in 253 aa, and to Serratia sp. MK1 accessory protein plaS SWALL:Q9X9D9 (EMBL:U37262) (251 aa) fasta scores: E(): 1.5e-07, 26.66% id in 210 aa. Also similar to ECA3425 (83.784% identity in 259 aa overlap).
   
 0.649
ECA1661
Hypothetical protein; No significant database matches.
    
 0.642
fklB
Similar to Escherichia coli, and Shigella flexneri fkbp-type 22 kDa peptidyl-prolyl cis-trans isomerase fklb or b4207 or sf4279 SWALL:FKBB_ECOLI (SWALL:P39311) (205 aa) fasta scores: E(): 1.8e-62, 82.92% id in 205 aa.
    
 
 0.634
fkpA
Similar to Escherichia coli fkbp-type peptidyl-prolyl cis-trans isomerase FkpA precursor FkpA or b3347 SWALL:FKBA_ECOLI (SWALL:P45523) (270 aa) fasta scores: E(): 9.4e-63, 73.13% id in 268 aa.
    
 
 0.634
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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