STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3865Similar to Yersinia pestis putative membrane protein ypo0485 SWALL:Q8ZIL1 (EMBL:AJ414143) (151 aa) fasta scores: E(): 1.8e-48, 85.06% id in 154 aa, and to Salmonella typhi putative membrane protein sty4898 SWALL:Q8Z0W0 (EMBL:AL627284) (157 aa) fasta scores: E(): 2.1e-43, 71.97% id in 157 aa. (156 aa)    
Predicted Functional Partners:
ECA3866
Similar to Yersinia pestis putative membrane protein ypo0484 or y3690 SWALL:Q8ZIL2 (EMBL:AJ414143) (266 aa) fasta scores: E(): 1.7e-82, 82.14% id in 252 aa, and to Salmonella typhi putative membrane protein sty4899 SWALL:Q8Z0V9 (EMBL:AL627284) (303 aa) fasta scores: E(): 1.1e-75, 70.49% id in 261 aa.
     0.981
dcuC
Anaerobic C4-dicarboxylate transporter; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri anaerobic c4-dicarboxylate transporter DcuC or b0621 or z0766 or ecs0660 or sf0659 SWALL:DCUC_ECOLI (SWALL:Q47134) (461 aa) fasta scores: E(): 3.1e-137, 81.25% id in 448 aa.
  
     0.647
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.565
ECA3867
Similar to Yersinia pestis putative lyse type translocator ypo0483 SWALL:Q8ZIL3 (EMBL:AJ414143) (204 aa) fasta scores: E(): 5.5e-66, 78.92% id in 204 aa, and to Pseudomonas aeruginosa hypothetical protein Pa2710 pa2710 SWALL:Q9I0D2 (EMBL:AE004699) (204 aa) fasta scores: E(): 4.4e-59, 74.87% id in 203 aa.
       0.521
menC
O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
  
     0.483
ECA2743
Similar to Escherichia coli hypothetical protein yech or b1906 SWALL:YECH_ECOLI (SWALL:P46887) (79 aa) fasta scores: E(): 5.8e-18, 62.02% id in 79 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yech or stm1936 or sty2144 SWALL:Q8XGI3 (EMBL:AE008786) (79 aa) fasta scores: E(): 1.1e-16, 59.49% id in 79 aa.
  
     0.441
ECA4401
Putative membrane protein; Similar to Yersinia pestis hypothetical membrane protein ypo4083 or y4100 SWALL:Y4I3_YERPE (SWALL:Q8Z9V7) (552 aa) fasta scores: E(): 2.4e-166, 80.07% id in 552 aa, and to Salmonella typhimurium hypothetical membrane protein yide or stm3807 SWALL:YIDE_SALTY (SWALL:Q8ZL04) (553 aa) fasta scores: E(): 5.2e-158, 76.5% id in 549 aa.
 
     0.441
frdC
Fumarate reductase 15 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
  
     0.421
ECA1814
Conserved hypothetical protein; Similar to Salmonella typhimurium, and Salmonella typhi hypothetical protein ycfp or stm1210 or sty1250 SWALL:Q8XGQ0 (EMBL:AE008752) (180 aa) fasta scores: E(): 8.5e-62, 82.77% id in 180 aa, and to Yersinia pestis hypothetical protein ypo1616 or y1776 SWALL:AAM85344 (EMBL:AJ414149) (180 aa) fasta scores: E(): 3.8e-61, 81.11% id in 180 aa; Belongs to the UPF0227 family.
  
     0.412
cutF
Similar to Escherichia coli copper homeostasis protein CutF precursor or NlpE or b0192 SWALL:CUTF_ECOLI (SWALL:P40710) (236 aa) fasta scores: E(): 8.9e-40, 49.55% id in 224 aa, and to Yersinia pestis putative copper homeostasis lipoprotein CutF or ypo1067 or y3110 SWALL:AAM86660 (EMBL:AJ414146) (242 aa) fasta scores: E(): 1.5e-46, 53.71% id in 229 aa.
  
     0.410
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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