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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa)    
Predicted Functional Partners:
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.995
ECA3763
Similar to Bacillus subtilis dihydrodipicolinate synthase DapA SWALL:DAPA_BACSU (SWALL:Q04796) (290 aa) fasta scores: E(): 2.9e-26, 34.16% id in 281 aa, and to Escherichia coli O6 putative dihydrodipicolinate synthase c0761 SWALL:AAN79234 (EMBL:AE016757) (295 aa) fasta scores: E(): 1.9e-75, 67.91% id in 293 aa; Belongs to the DapA family.
 
 
 0.994
ECA4425
Putative dihydrodipicolinate synthetase; Similar to Bradyrhizobium japonicum Bll7272 protein bll7272 SWALL:BAC52537 (EMBL:AP005961) (291 aa) fasta scores: E(): 3.2e-70, 65.97% id in 288 aa, and to Pseudomonas aeruginosa probable dihydrodipicolinate synthetase pa0223 SWALL:Q9I6R5 (EMBL:AE004460) (293 aa) fasta scores: E(): 8.8e-24, 32.29% id in 288 aa.
 
 
 0.994
ECA1002
Putative dihydrodipicolinate synthase; Similar to Escherichia coli, and Shigella flexneri dihydrodipicolinate synthase DapA or b2478 or sf2521 SWALL:DAPA_ECOLI (SWALL:P05640) (292 aa) fasta scores: E(): 2.8e-20, 30.45% id in 289 aa, and to Ralstonia solanacearum dihydrodipicolinate synthase dapa or rsc1145 or rs04756 SWALL:DAPA_RALSO (SWALL:Q8Y099) (294 aa) fasta scores: E(): 2.5e-26, 30.71% id in 280 aa; Belongs to the DapA family.
 
 
 0.993
dapD
Similar to Escherichia coli, and Shigella flexneri 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase DapD or b0166 or sf0156 SWALL:DAPD_ECOLI (SWALL:P03948) (274 aa) fasta scores: E(): 4.7e-99, 91.94% id in 273 aa, and to Salmonella typhimurium 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase DapD or stm0213 SWALL:Q8ZRP4 (EMBL:AE008704) (274 aa) fasta scores: E(): 2e-98, 90.11% id in 273 aa; Belongs to the transferase hexapeptide repeat family.
 
 
 0.992
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
  
 0.781
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
  
 0.774
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
   
 0.766
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.720
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
    0.662
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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