STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhaRSimilar to Escherichia coli transcriptional activator protein NhaR or AntO or b0020 SWALL:NHAR_ECOLI (SWALL:P10087) (301 aa) fasta scores: E(): 2.3e-94, 76.87% id in 294 aa; Belongs to the LysR transcriptional regulatory family. (306 aa)    
Predicted Functional Partners:
nhaA
Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
  
  
 0.793
cstA
Similar to Escherichia coli carbon starvation protein A CstA or b0598 SWALL:CSTA_ECOLI (SWALL:P15078) (701 aa) fasta scores: E(): 8.8e-164, 60.67% id in 684 aa.
      
 0.549
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
      
 0.544
csrA
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Belongs to the CsrA/RsmA family.
     
 0.528
hfq
Putative phage-related protein (host factor-I protein); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
      
 0.505
malF
Similar to Escherichia coli maltose transport system permease protein MalF or b4033 SWALL:MALF_ECOLI (SWALL:P02916) (514 aa) fasta scores: E(): 5.9e-36, 39.71% id in 277 aa, and to Yersinia pestis putative maltodextrin transport permease ypo0855 or MalF or y3240 SWALL:Q8ZHN5 (EMBL:AJ414145) (435 aa) fasta scores: E(): 6.8e-138, 81.86% id in 419 aa.
      
 0.475
sfsB
Sugar fermentation stimulation protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri sugar fermentation stimulation protein B SfsB or Nlp or sfs7 or b3188 or c3946 or z4551 or ecs4067 or sf3228 SWALL:SFSB_ECOLI (SWALL:P18837) (92 aa) fasta scores: E(): 5.7e-20, 70.88% id in 79 aa. Also similar to ECA0513 (71.233% id. in 73 aa overlap), and to ECA0966 (72.368% id. in 76 aa overlap), and to ECA3206 (76.119% id. in 67 aa overlap.).
      
 0.474
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
      
 0.474
uspA
Universal stress protein A; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri universal stress protein A UspA or b3495 or c4293 or z4895 or ecs4367 or sf3526 SWALL:USPA_ECOLI (SWALL:P28242) (143 aa) fasta scores: E(): 6.7e-47, 94.36% id in 142 aa.
      
 0.454
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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