| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA0413 | nhaA | ECA0413 | ECA3880 | Putative intergrase (pseudogene); This hit extended beyond the end of the feature by 1 aa and was clipped; HMMPfam hit to PF00589, DE Phage integrase family, score 0.0058. | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.579 |
| ECA0784 | kefB | ECA0784 | ECA4056 | Putative sodium/hydrogen antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | Glutathione-regulated potassium-efflux system protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | 0.518 |
| ECA0784 | nhaA | ECA0784 | ECA3880 | Putative sodium/hydrogen antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.416 |
| ECA1182 | kefB | ECA1182 | ECA4056 | Putative transport protein; Similar to Yersinia pestis putative potassium antiporter RosB or ypo3094 or y1086 SWALL:Q8ZCA2 (EMBL:AJ414155) (563 aa) fasta scores: E(): 7.3e-162, 81.52% id in 563 aa, and to Salmonella typhi putative transport protein sty0536 SWALL:Q8Z8S9 (EMBL:AL627267) (558 aa) fasta scores: E(): 1.5e-155, 79.27% id in 555 aa; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Glutathione-regulated potassium-efflux system protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | 0.671 |
| ECA1182 | nhaA | ECA1182 | ECA3880 | Putative transport protein; Similar to Yersinia pestis putative potassium antiporter RosB or ypo3094 or y1086 SWALL:Q8ZCA2 (EMBL:AJ414155) (563 aa) fasta scores: E(): 7.3e-162, 81.52% id in 563 aa, and to Salmonella typhi putative transport protein sty0536 SWALL:Q8Z8S9 (EMBL:AL627267) (558 aa) fasta scores: E(): 1.5e-155, 79.27% id in 555 aa; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.418 |
| ECA1598 | nhaA | ECA1598 | ECA3880 | Conserved hypothetical protein; Similar to Bacillus anthracis pxo2-73 bxb0100 SWALL:Q9RMW1 (EMBL:AF188935) (541 aa) fasta scores: E(): 2.2e-22, 31.18% id in 356 aa, and to Streptococcus agalactiae protein of unknown function sag1992 SWALL:AAN00852 (EMBL:AE014281) (518 aa) fasta scores: E(): 8.7e-09, 32.91% id in 237 aa. | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.579 |
| dnaJ | dnaK | ECA3881 | ECA3882 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| dnaJ | kefB | ECA3881 | ECA4056 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Glutathione-regulated potassium-efflux system protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | 0.493 |
| dnaJ | nhaA | ECA3881 | ECA3880 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.468 |
| dnaK | dnaJ | ECA3882 | ECA3881 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.999 |
| dnaK | nhaA | ECA3882 | ECA3880 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.420 |
| kefB | ECA0784 | ECA4056 | ECA0784 | Glutathione-regulated potassium-efflux system protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | Putative sodium/hydrogen antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.518 |
| kefB | ECA1182 | ECA4056 | ECA1182 | Glutathione-regulated potassium-efflux system protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | Putative transport protein; Similar to Yersinia pestis putative potassium antiporter RosB or ypo3094 or y1086 SWALL:Q8ZCA2 (EMBL:AJ414155) (563 aa) fasta scores: E(): 7.3e-162, 81.52% id in 563 aa, and to Salmonella typhi putative transport protein sty0536 SWALL:Q8Z8S9 (EMBL:AL627267) (558 aa) fasta scores: E(): 1.5e-155, 79.27% id in 555 aa; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.671 |
| kefB | dnaJ | ECA4056 | ECA3881 | Glutathione-regulated potassium-efflux system protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.493 |
| kefB | nhaA | ECA4056 | ECA3880 | Glutathione-regulated potassium-efflux system protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | 0.561 |
| nhaA | ECA0413 | ECA3880 | ECA0413 | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | Putative intergrase (pseudogene); This hit extended beyond the end of the feature by 1 aa and was clipped; HMMPfam hit to PF00589, DE Phage integrase family, score 0.0058. | 0.579 |
| nhaA | ECA0784 | ECA3880 | ECA0784 | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | Putative sodium/hydrogen antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.416 |
| nhaA | ECA1182 | ECA3880 | ECA1182 | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | Putative transport protein; Similar to Yersinia pestis putative potassium antiporter RosB or ypo3094 or y1086 SWALL:Q8ZCA2 (EMBL:AJ414155) (563 aa) fasta scores: E(): 7.3e-162, 81.52% id in 563 aa, and to Salmonella typhi putative transport protein sty0536 SWALL:Q8Z8S9 (EMBL:AL627267) (558 aa) fasta scores: E(): 1.5e-155, 79.27% id in 555 aa; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.418 |
| nhaA | ECA1598 | ECA3880 | ECA1598 | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | Conserved hypothetical protein; Similar to Bacillus anthracis pxo2-73 bxb0100 SWALL:Q9RMW1 (EMBL:AF188935) (541 aa) fasta scores: E(): 2.2e-22, 31.18% id in 356 aa, and to Streptococcus agalactiae protein of unknown function sag1992 SWALL:AAN00852 (EMBL:AE014281) (518 aa) fasta scores: E(): 8.7e-09, 32.91% id in 237 aa. | 0.579 |
| nhaA | dnaJ | ECA3880 | ECA3881 | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.468 |