STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhaANa(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (393 aa)    
Predicted Functional Partners:
nhaR
Similar to Escherichia coli transcriptional activator protein NhaR or AntO or b0020 SWALL:NHAR_ECOLI (SWALL:P10087) (301 aa) fasta scores: E(): 2.3e-94, 76.87% id in 294 aa; Belongs to the LysR transcriptional regulatory family.
  
  
 0.793
ECA0413
Putative intergrase (pseudogene); This hit extended beyond the end of the feature by 1 aa and was clipped; HMMPfam hit to PF00589, DE Phage integrase family, score 0.0058.
   
    0.579
ECA1598
Conserved hypothetical protein; Similar to Bacillus anthracis pxo2-73 bxb0100 SWALL:Q9RMW1 (EMBL:AF188935) (541 aa) fasta scores: E(): 2.2e-22, 31.18% id in 356 aa, and to Streptococcus agalactiae protein of unknown function sag1992 SWALL:AAN00852 (EMBL:AE014281) (518 aa) fasta scores: E(): 8.7e-09, 32.91% id in 237 aa.
   
    0.579
kefB
Glutathione-regulated potassium-efflux system protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
 
   
 0.561
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
       0.468
nhaB
Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
  
   
 0.445
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  
 0.420
ECA1182
Putative transport protein; Similar to Yersinia pestis putative potassium antiporter RosB or ypo3094 or y1086 SWALL:Q8ZCA2 (EMBL:AJ414155) (563 aa) fasta scores: E(): 7.3e-162, 81.52% id in 563 aa, and to Salmonella typhi putative transport protein sty0536 SWALL:Q8Z8S9 (EMBL:AL627267) (558 aa) fasta scores: E(): 1.5e-155, 79.27% id in 555 aa; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.418
ECA0784
Putative sodium/hydrogen antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  
  
 0.416
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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