node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ECA3436 | dnaJ | ECA3436 | ECA3881 | Putative chaperone; Similar to Thermus thermophilus ClpB protein ClpB SWALL:CLPB_THETH (SWALL:Q9RA63) (854 aa) fasta scores: E(): 7e-69, 37.97% id in 869 aa, and to Yersinia pestis clp ATPase ClpB2 or ypo3599 or ClpB or y0275 SWALL:Q8ZB30 (EMBL:AJ414157) (867 aa) fasta scores: E(): 6.3e-209, 68.66% id in 868 aa; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.727 |
ECA3436 | dnaK | ECA3436 | ECA3882 | Putative chaperone; Similar to Thermus thermophilus ClpB protein ClpB SWALL:CLPB_THETH (SWALL:Q9RA63) (854 aa) fasta scores: E(): 7e-69, 37.97% id in 869 aa, and to Yersinia pestis clp ATPase ClpB2 or ypo3599 or ClpB or y0275 SWALL:Q8ZB30 (EMBL:AJ414157) (867 aa) fasta scores: E(): 6.3e-209, 68.66% id in 868 aa; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.885 |
ECA3436 | groL | ECA3436 | ECA0625 | Putative chaperone; Similar to Thermus thermophilus ClpB protein ClpB SWALL:CLPB_THETH (SWALL:Q9RA63) (854 aa) fasta scores: E(): 7e-69, 37.97% id in 869 aa, and to Yersinia pestis clp ATPase ClpB2 or ypo3599 or ClpB or y0275 SWALL:Q8ZB30 (EMBL:AJ414157) (867 aa) fasta scores: E(): 6.3e-209, 68.66% id in 868 aa; Belongs to the ClpA/ClpB family. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.689 |
ECA3436 | groS | ECA3436 | ECA0624 | Putative chaperone; Similar to Thermus thermophilus ClpB protein ClpB SWALL:CLPB_THETH (SWALL:Q9RA63) (854 aa) fasta scores: E(): 7e-69, 37.97% id in 869 aa, and to Yersinia pestis clp ATPase ClpB2 or ypo3599 or ClpB or y0275 SWALL:Q8ZB30 (EMBL:AJ414157) (867 aa) fasta scores: E(): 6.3e-209, 68.66% id in 868 aa; Belongs to the ClpA/ClpB family. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.624 |
ECA3436 | grpE | ECA3436 | ECA0842 | Putative chaperone; Similar to Thermus thermophilus ClpB protein ClpB SWALL:CLPB_THETH (SWALL:Q9RA63) (854 aa) fasta scores: E(): 7e-69, 37.97% id in 869 aa, and to Yersinia pestis clp ATPase ClpB2 or ypo3599 or ClpB or y0275 SWALL:Q8ZB30 (EMBL:AJ414157) (867 aa) fasta scores: E(): 6.3e-209, 68.66% id in 868 aa; Belongs to the ClpA/ClpB family. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.705 |
ECA3436 | htpG | ECA3436 | ECA1179 | Putative chaperone; Similar to Thermus thermophilus ClpB protein ClpB SWALL:CLPB_THETH (SWALL:Q9RA63) (854 aa) fasta scores: E(): 7e-69, 37.97% id in 869 aa, and to Yersinia pestis clp ATPase ClpB2 or ypo3599 or ClpB or y0275 SWALL:Q8ZB30 (EMBL:AJ414157) (867 aa) fasta scores: E(): 6.3e-209, 68.66% id in 868 aa; Belongs to the ClpA/ClpB family. | Chaperone protein; Molecular chaperone. Has ATPase activity. | 0.666 |
clpA | dnaJ | ECA2656 | ECA3881 | ATP-dependent CLP protease ATP-binding subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ATP-dependent Clp protease ATP-binding subunit ClpA or LopD or b0882 or c1019 or z1119 or ecs0968 SWALL:CLPA_ECOLI (SWALL:P15716) (758 aa) fasta scores: E(): 0, 90.23% id in 758 aa; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.869 |
clpA | dnaK | ECA2656 | ECA3882 | ATP-dependent CLP protease ATP-binding subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ATP-dependent Clp protease ATP-binding subunit ClpA or LopD or b0882 or c1019 or z1119 or ecs0968 SWALL:CLPA_ECOLI (SWALL:P15716) (758 aa) fasta scores: E(): 0, 90.23% id in 758 aa; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.884 |
clpA | groL | ECA2656 | ECA0625 | ATP-dependent CLP protease ATP-binding subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ATP-dependent Clp protease ATP-binding subunit ClpA or LopD or b0882 or c1019 or z1119 or ecs0968 SWALL:CLPA_ECOLI (SWALL:P15716) (758 aa) fasta scores: E(): 0, 90.23% id in 758 aa; Belongs to the ClpA/ClpB family. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.799 |
clpA | groS | ECA2656 | ECA0624 | ATP-dependent CLP protease ATP-binding subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ATP-dependent Clp protease ATP-binding subunit ClpA or LopD or b0882 or c1019 or z1119 or ecs0968 SWALL:CLPA_ECOLI (SWALL:P15716) (758 aa) fasta scores: E(): 0, 90.23% id in 758 aa; Belongs to the ClpA/ClpB family. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.624 |
clpA | grpE | ECA2656 | ECA0842 | ATP-dependent CLP protease ATP-binding subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ATP-dependent Clp protease ATP-binding subunit ClpA or LopD or b0882 or c1019 or z1119 or ecs0968 SWALL:CLPA_ECOLI (SWALL:P15716) (758 aa) fasta scores: E(): 0, 90.23% id in 758 aa; Belongs to the ClpA/ClpB family. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.859 |
clpA | htpG | ECA2656 | ECA1179 | ATP-dependent CLP protease ATP-binding subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ATP-dependent Clp protease ATP-binding subunit ClpA or LopD or b0882 or c1019 or z1119 or ecs0968 SWALL:CLPA_ECOLI (SWALL:P15716) (758 aa) fasta scores: E(): 0, 90.23% id in 758 aa; Belongs to the ClpA/ClpB family. | Chaperone protein; Molecular chaperone. Has ATPase activity. | 0.646 |
clpB | dnaJ | ECA3345 | ECA3881 | ClpB protein (heat shock protein f84.1); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.851 |
clpB | dnaK | ECA3345 | ECA3882 | ClpB protein (heat shock protein f84.1); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.939 |
clpB | groL | ECA3345 | ECA0625 | ClpB protein (heat shock protein f84.1); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.829 |
clpB | groS | ECA3345 | ECA0624 | ClpB protein (heat shock protein f84.1); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.624 |
clpB | grpE | ECA3345 | ECA0842 | ClpB protein (heat shock protein f84.1); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.838 |
clpB | htpG | ECA3345 | ECA1179 | ClpB protein (heat shock protein f84.1); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein; Molecular chaperone. Has ATPase activity. | 0.666 |
dnaJ | ECA3436 | ECA3881 | ECA3436 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Putative chaperone; Similar to Thermus thermophilus ClpB protein ClpB SWALL:CLPB_THETH (SWALL:Q9RA63) (854 aa) fasta scores: E(): 7e-69, 37.97% id in 869 aa, and to Yersinia pestis clp ATPase ClpB2 or ypo3599 or ClpB or y0275 SWALL:Q8ZB30 (EMBL:AJ414157) (867 aa) fasta scores: E(): 6.3e-209, 68.66% id in 868 aa; Belongs to the ClpA/ClpB family. | 0.727 |
dnaJ | clpA | ECA3881 | ECA2656 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | ATP-dependent CLP protease ATP-binding subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ATP-dependent Clp protease ATP-binding subunit ClpA or LopD or b0882 or c1019 or z1119 or ecs0968 SWALL:CLPA_ECOLI (SWALL:P15716) (758 aa) fasta scores: E(): 0, 90.23% id in 758 aa; Belongs to the ClpA/ClpB family. | 0.869 |