STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3886Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa. (362 aa)    
Predicted Functional Partners:
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
 0.999
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
 0.999
rcsC
Two-component system sensor protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
 0.998
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
 0.998
hrpX
Two-component sensor kinase; Similar to Erwinia chrysanthemi HrpX SWALL:Q8KUM4 (EMBL:AF448202) (450 aa) fasta scores: E(): 3.4e-115, 68.25% id in 441 aa, and to Erwinia amylovora sensor kinase HrpX SWALL:Q9X3S8 (EMBL:AF083877) (494 aa) fasta scores: E(): 9.5e-100, 56.13% id in 481 aa.
  
 0.998
ECA3549
Putative signaling protein; Similar to Vibrio vulnificus response regulator VieA vv21511 SWALL:AAO08375 (EMBL:AE016813) (386 aa) fasta scores: E(): 5.5e-16, 30.04% id in 233 aa, and to Anabaena sp. two-component response regulator alr1230 SWALL:Q8YXI3 (EMBL:AP003585) (403 aa) fasta scores: E(): 7.6e-16, 30.35% id in 224 aa.
 
 0.998
ECA3625
Conserved hypothetical protein; Similar to Agrobacterium tumefaciens McpA SWALL:O68016 (EMBL:AF010180) (579 aa) fasta scores: E(): 1.9e-31, 36.54% id in 249 aa, and to Xanthomonas axonopodis chemotaxis protein mcpa or xac1746 SWALL:Q8PLP7 (EMBL:AE011806) (684 aa) fasta scores: E(): 1.3e-35, 36.56% id in 268 aa.
 
0.998
ECA2433
Putative signaling protein; Similar to Caulobacter crescentus sensory box/ggdef family protein cc3094 SWALL:Q9A3V7 (EMBL:AE005972) (748 aa) fasta scores: E(): 3.4e-74, 34.06% id in 731 aa, and to Rhizobium loti hypothetical protein Mll7787 SWALL:Q984Y8 (EMBL:AP003012) (724 aa) fasta scores: E(): 1.7e-66, 37.17% id in 581 aa.
 
0.997
ECA3270
Putative exported protein; Similar to Rhizobium meliloti hypothetical protein r00959 or smc00038 SWALL:Q92KJ3 (EMBL:AL591785) (772 aa) fasta scores: E(): 1e-48, 35.35% id in 461 aa, and to Xanthomonas campestris c-di-gmp phosphodiesterase A PdeA or xcc1865 SWALL:Q8P9J8 (EMBL:AE012289) (726 aa) fasta scores: E(): 1.1e-41, 31.81% id in 462 aa.
 
 
0.991
expM
Response regulator; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.
 
 0.990
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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