STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3898Conserved hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (179 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.900
rof
Modulator of rho-dependent transcription termination; Similar to Escherichia coli, and Shigella flexneri Rof protein or b0189 or sf0179 SWALL:ROF_ECOLI (SWALL:P52098) (84 aa) fasta scores: E(): 3.4e-22, 70.23% id in 84 aa, and to Salmonella typhimurium modulator of rho-dependent transcription termination Rof or stm0237 SWALL:Q8ZRN4 (EMBL:AE008706) (86 aa) fasta scores: E(): 2.9e-20, 66.27% id in 86 aa.
  
     0.606
gpmB
Probable phosphoglycerate mutase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri probable phosphoglycerate mutase GpmB or b4395 or z5997 or ecs5353 or sf4427 SWALL:GPMB_ECOLI (SWALL:P36942) (215 aa) fasta scores: E(): 1.6e-61, 74.07% id in 216 aa.
     
 0.584
ECA1447
Putative exported protein; Similar to Escherichia coli hypothetical protein ymcb precursor ymcb or b0985 SWALL:YMCB_ECOLI (SWALL:P75883) (248 aa) fasta scores: E(): 3.6e-08, 31% id in 258 aa, and to Shigella flexneri orf, conserved hypothetical protein ymcb or sf0987 SWALL:AAN42615 (EMBL:AE015127) (248 aa) fasta scores: E(): 3.6e-08, 32.04% id in 259 aa.
  
     0.544
smp
Putative membrane protein; Similar to Escherichia coli, and Shigella flexneri protein Smp precursor Smp or b4387 or sf4419 SWALL:SMP_ECOLI (SWALL:P18838) (214 aa) fasta scores: E(): 3.9e-52, 65.72% id in 213 aa.
  
     0.538
UspE
Similar to Salmonella typhimurium putative universal stress protein ydaa or stm1661 SWALL:Q8ZP84 (EMBL:AE008773) (315 aa) fasta scores: E(): 3e-104, 81.58% id in 315 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri protein ydaa or b1333 or c1806 or z2435 or ecs1914 or sf1837 SWALL:AAN43399 (EMBL:AE000231) (325 aa) fasta scores: E(): 3.6e-102, 80% id in 315 aa.
  
     0.497
ECA3257
Similar to Yersinia pestis two-component system sensor kinase ypo2916 or y1313 SWALL:Q8ZCQ5 (EMBL:AJ414154) (483 aa) fasta scores: E(): 5.4e-148, 79.91% id in 478 aa, and to Salmonella typhimurium putative sensory kinase in regulatory system yfhk or stm2564 SWALL:Q8ZN30 (EMBL:AE008816) (480 aa) fasta scores: E(): 6.7e-134, 73.67% id in 471 aa.
  
     0.491
ECA2468
Putative exported protein; Similar to Salmonella typhimurium putative outer membrane protein ycfr or stm1214 SWALL:Q8ZQ03 (EMBL:AE008753) (85 aa) fasta scores: E(): 2.6e-06, 48.23% id in 85 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein ybij precursor ybij or b0802 or c0886 or sf0752 SWALL:YBIJ_ECOLI (SWALL:P41038) (86 aa) fasta scores: E(): 1.3e-05, 52.32% id in 86 aa.
  
     0.480
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
     0.473
ftsN
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
     0.466
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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