STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpRTrp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (110 aa)    
Predicted Functional Partners:
ECA4348
Similar to Yersinia pestis putative membrane protein ypo3816a or y0414 SWALL:Q8ZAI5 (EMBL:AJ414159) (90 aa) fasta scores: E(): 1.2e-22, 71.59% id in 88 aa, and to Shigella flexneri orf, conserved hypothetical protein yhhl or sf3484 SWALL:AAN44943 (EMBL:AE015356) (90 aa) fasta scores: E(): 5.6e-22, 69.41% id in 85 aa.
  
    0.816
matP
Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.772
ECA2528
Similar to Yersinia pestis hypothetical protein ypo2038 or y2274 SWALL:AAM85834 (EMBL:AJ414151) (186 aa) fasta scores: E(): 2.8e-45, 67.22% id in 180 aa, and to Escherichia coli hypothetical protein ycdy or b1035 SWALL:YCDY_ECOLI (SWALL:P75915) (184 aa) fasta scores: E(): 1.1e-41, 60.42% id in 187 aa.
  
    0.766
ECA0979
Putative exported protein; Similar to Salmonella typhimurium putative periplasmic protein yggn or stm3107 SWALL:Q8ZM42 (EMBL:AE008842) (239 aa) fasta scores: E(): 1.6e-48, 59.41% id in 239 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yggn or b2958 or c3544 or z4303 or ecs3834 SWALL:YGGN_ECOLI (SWALL:P46143) (239 aa) fasta scores: E(): 1.8e-48, 58.99% id in 239 aa.
  
     0.711
ECA2377
Similar to Yersinia pestis hypothetical protein ypo1774 or y2534 SWALL:YH74_YERPE (SWALL:Q8ZFE0) (85 aa) fasta scores: E(): 1.1e-10, 53.84% id in 78 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yoah or b1811 or c2216 or z2854 or ecs2520 SWALL:YOAH_ECOLI (SWALL:P76260) (59 aa) fasta scores: E(): 1.7e-10, 67.24% id in 58 aa; Belongs to the UPF0181 family.
  
     0.708
yfeE
Putative membrane protein; Similar to Yersinia pestis putative yfeabcd regulator YfeE or ypo2445 or y1891 SWALL:YFEE_YERPE (SWALL:Q56956) (184 aa) fasta scores: E(): 1.8e-48, 63.73% id in 182 aa, and to Salmonella typhimurium, and Salmonella typhi putative regulator ynib or stm1323 or sty1788 SWALL:Q8XFB7 (EMBL:AE008757) (178 aa) fasta scores: E(): 6.8e-47, 63.33% id in 180 aa.
  
     0.705
slt
Similar to Escherichia coli soluble lytic murein transglycosylase precursor Slt or SltY or b4392 SWALL:SLT_ECOLI (SWALL:P03810) (645 aa) fasta scores: E(): 1.6e-161, 60.31% id in 645 aa.
 
     0.697
mukE
Killing factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.687
ECA2527
Similar to Yersinia pestis putative lipoprotein ypo2039 SWALL:Q8ZEW4 (EMBL:AJ414151) (187 aa) fasta scores: E(): 2.6e-47, 73.93% id in 188 aa, and to Escherichia coli, and Shigella flexneri putative lipoprotein yceb precursor yceb or b1063 or sf1069 SWALL:YCEB_ECOLI (SWALL:P09995) (186 aa) fasta scores: E(): 2.3e-40, 65.02% id in 183 aa.
  
     0.677
mukF
Killing factor; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.677
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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