STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbpFructose-1,6-bisphosphatase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri fructose-1,6-bisphosphatase Fbp or Fdp or b4232 or c5329 or sf4258 SWALL:F16P_ECOLI (SWALL:P09200) (332 aa) fasta scores: E(): 2.6e-110, 86.82% id in 334 aa. (334 aa)    
Predicted Functional Partners:
tktA1
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.951
pgi
Glucose-6-phosphate isomerase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucose-6-phosphate isomerase Pgi or b4025 or z5623 or ecs5008 SWALL:G6PI_ECOLI (SWALL:P11537) (549 aa) fasta scores: E(): 1.4e-193, 86.86% id in 548 aa.
  
 
 0.941
ECA0338
Probable sugar-bisphosphate aldolase; Similar to Lactobacillus casei D-fructose-1,6-biphosphate aldolase sorG SWALL:Q9RGG1 (EMBL:AF129168) (276 aa) fasta scores: E(): 1.9e-37, 41.97% id in 274 aa, and to Escherichia coli O6 putative aldolase c4483 SWALL:AAN82919 (EMBL:AE016769) (286 aa) fasta scores: E(): 8.4e-89, 80.06% id in 286 aa.
  
 
 0.927
ECA0339
Probable sugar-bisphosphate aldolase; Similar to Escherichia coli tagatose-1,6-bisphosphate aldolase GatY or b2096 SWALL:GATY_ECOLI (SWALL:P37192) (284 aa) fasta scores: E(): 1.8e-26, 36.36% id in 286 aa, and to Escherichia coli O6 putative aldolase c4484 SWALL:AAN82920 (EMBL:AE016769) (283 aa) fasta scores: E(): 7.5e-58, 59.01% id in 283 aa.
  
 
 0.927
fbaA
Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.927
fruK
1-phosphofructokinase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri 1-phosphofructokinase FruK or Fpk or b2168 or c2703 or z3426 or ecs3060 or sf2253 SWALL:K1PF_ECOLI (SWALL:P23539) (312 aa) fasta scores: E(): 7.8e-108, 90.7% id in 312 aa; Belongs to the carbohydrate kinase PfkB family.
    
 0.923
ECA2352
Putative 6-phosphofructokinase isozyme II; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
    
 0.921
pfkA
6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.921
glpX
Putative glycerol metabolic protein; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri protein GlpX or b3925 or c4877 or sf4003 SWALL:GLPX_ECOLI (SWALL:P28860) (336 aa) fasta scores: E(): 7e-102, 86.6% id in 336 aa.
    
 0.920
talA
Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.919
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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