STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
hflCPutative phage-related protein; HflC and HflK could regulate a protease. (331 aa)    
Predicted Functional Partners:
hflK
Putative phage-related protein; HflC and HflK could encode or regulate a protease.
 
 
0.994
hflB
Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.930
hflX
Putative GTP-binding phage-related protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.875
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.765
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
  
 0.708
ECA3930
Similar to Yersinia pestis putative membrane protein ypo0377 SWALL:Q8ZIV8 (EMBL:AJ414142) (66 aa) fasta scores: E(): 4e-19, 78.46% id in 65 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yjet or b4176 or z5783 or ecs5152 or sf4331 SWALL:AAN45748 (EMBL:U14003) (65 aa) fasta scores: E(): 1.8e-17, 70.76% id in 65 aa.
     
 0.602
hfq
Putative phage-related protein (host factor-I protein); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
  
  
 0.578
engB
Probable GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
  
    0.576
wzb
Probable protein-tyrosine-phosphatase; Similar to Salmonella typhimurium low molecular weight protein-tyrosine-phosphatase Wzb or stm2117 SWALL:WZB_SALTY (SWALL:Q9F7B2) (149 aa) fasta scores: E(): 1.5e-34, 65.73% id in 143 aa, and to Erwinia amylovora probable low molecular weight protein-tyrosine-phosphatase AmsI SWALL:AMSI_ERWAM (SWALL:Q46630) (144 aa) fasta scores: E(): 5.8e-37, 69.44% id in 144 aa.
  
    0.565
ECA1195
Similar to Yersinia pestis putative membrane protein ypo3084 or y1095 SWALL:Q8ZCA9 (EMBL:AJ414155) (149 aa) fasta scores: E(): 2.4e-35, 60% id in 150 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein ybbj or b0488 or sf0433 SWALL:YBBJ_ECOLI (SWALL:P75709) (151 aa) fasta scores: E(): 2e-34, 59.73% id in 149 aa.
 
 
 0.530
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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