| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA3930 | hflC | ECA3930 | ECA3931 | Similar to Yersinia pestis putative membrane protein ypo0377 SWALL:Q8ZIV8 (EMBL:AJ414142) (66 aa) fasta scores: E(): 4e-19, 78.46% id in 65 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yjet or b4176 or z5783 or ecs5152 or sf4331 SWALL:AAN45748 (EMBL:U14003) (65 aa) fasta scores: E(): 1.8e-17, 70.76% id in 65 aa. | Putative phage-related protein; HflC and HflK could regulate a protease. | 0.571 |
| ECA3930 | hflK | ECA3930 | ECA3932 | Similar to Yersinia pestis putative membrane protein ypo0377 SWALL:Q8ZIV8 (EMBL:AJ414142) (66 aa) fasta scores: E(): 4e-19, 78.46% id in 65 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yjet or b4176 or z5783 or ecs5152 or sf4331 SWALL:AAN45748 (EMBL:U14003) (65 aa) fasta scores: E(): 1.8e-17, 70.76% id in 65 aa. | Putative phage-related protein; HflC and HflK could encode or regulate a protease. | 0.642 |
| ECA3930 | hflX | ECA3930 | ECA3933 | Similar to Yersinia pestis putative membrane protein ypo0377 SWALL:Q8ZIV8 (EMBL:AJ414142) (66 aa) fasta scores: E(): 4e-19, 78.46% id in 65 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yjet or b4176 or z5783 or ecs5152 or sf4331 SWALL:AAN45748 (EMBL:U14003) (65 aa) fasta scores: E(): 1.8e-17, 70.76% id in 65 aa. | Putative GTP-binding phage-related protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.477 |
| glpG | hflB | ECA4138 | ECA0698 | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.587 |
| glpG | hflC | ECA4138 | ECA3931 | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Putative phage-related protein; HflC and HflK could regulate a protease. | 0.569 |
| glpG | hflK | ECA4138 | ECA3932 | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Putative phage-related protein; HflC and HflK could encode or regulate a protease. | 0.569 |
| hflB | glpG | ECA0698 | ECA4138 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.587 |
| hflB | hflC | ECA0698 | ECA3931 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative phage-related protein; HflC and HflK could regulate a protease. | 0.890 |
| hflB | hflK | ECA0698 | ECA3932 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative phage-related protein; HflC and HflK could encode or regulate a protease. | 0.930 |
| hflB | hflX | ECA0698 | ECA3933 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative GTP-binding phage-related protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.503 |
| hflB | hfq | ECA0698 | ECA3934 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative phage-related protein (host factor-I protein); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.506 |
| hflB | miaA | ECA0698 | ECA3935 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.596 |
| hflB | nuoC | ECA0698 | ECA3026 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.530 |
| hflB | tig | ECA0698 | ECA1147 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.585 |
| hflB | yidC | ECA0698 | ECA4445 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.497 |
| hflC | ECA3930 | ECA3931 | ECA3930 | Putative phage-related protein; HflC and HflK could regulate a protease. | Similar to Yersinia pestis putative membrane protein ypo0377 SWALL:Q8ZIV8 (EMBL:AJ414142) (66 aa) fasta scores: E(): 4e-19, 78.46% id in 65 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yjet or b4176 or z5783 or ecs5152 or sf4331 SWALL:AAN45748 (EMBL:U14003) (65 aa) fasta scores: E(): 1.8e-17, 70.76% id in 65 aa. | 0.571 |
| hflC | glpG | ECA3931 | ECA4138 | Putative phage-related protein; HflC and HflK could regulate a protease. | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.569 |
| hflC | hflB | ECA3931 | ECA0698 | Putative phage-related protein; HflC and HflK could regulate a protease. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.890 |
| hflC | hflK | ECA3931 | ECA3932 | Putative phage-related protein; HflC and HflK could regulate a protease. | Putative phage-related protein; HflC and HflK could encode or regulate a protease. | 0.988 |
| hflC | hflX | ECA3931 | ECA3933 | Putative phage-related protein; HflC and HflK could regulate a protease. | Putative GTP-binding phage-related protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.791 |