Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hflKPutative phage-related protein; HflC and HflK could encode or regulate a protease. (417 aa)    
Predicted Functional Partners:
hflC
Putative phage-related protein; HflC and HflK could regulate a protease.
 
 
0.994
hflB
Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.956
hflX
Putative GTP-binding phage-related protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.927
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.765
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
  
 0.732
ECA3930
Similar to Yersinia pestis putative membrane protein ypo0377 SWALL:Q8ZIV8 (EMBL:AJ414142) (66 aa) fasta scores: E(): 4e-19, 78.46% id in 65 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yjet or b4176 or z5783 or ecs5152 or sf4331 SWALL:AAN45748 (EMBL:U14003) (65 aa) fasta scores: E(): 1.8e-17, 70.76% id in 65 aa.
 
   
 0.668
yidC
Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
 
 0.632
ECA1763
Similar to Salmonella typhi putative membrane protein sty1112 SWALL:Q8Z7R5 (EMBL:AL627269) (219 aa) fasta scores: E(): 2.3e-60, 77.16% id in 219 aa, and to Escherichia coli O157:H7 putative carrier/transport protein ycca or z1322 or ecs1054 SWALL:Q8XD81 (EMBL:AE005287) (219 aa) fasta scores: E(): 4e-60, 76.25% id in 219 aa; Belongs to the BI1 family.
  
  
 0.617
hfq
Putative phage-related protein (host factor-I protein); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
  
  
 0.564
ECA1858
Hypothetical protein; No significant database matches.
  
 
 0.542
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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