STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA3994Similar to Salmonella typhi hypothetical protein yrdb or sty4397 SWALL:Q8Z1W4 (EMBL:AL627282) (85 aa) fasta scores: E(): 1.2e-18, 58.82% id in 85 aa, and to Escherichia coli hypothetical protein yrdb or b3280 SWALL:YRDB_ECOLI (SWALL:P45795) (85 aa) fasta scores: E(): 1.7e-18, 58.02% id in 81 aa. (85 aa)    
Predicted Functional Partners:
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.867
tsaC
Putative DNA topoisomerase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
     
 0.770
smg
Conserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri protein Smg or b3284 or sf3316 SWALL:SMG_ECOLI (SWALL:P30853) (157 aa) fasta scores: E(): 6.6e-48, 76.43% id in 157 aa, and to Salmonella typhimurium, and Salmonella typhi Smg protein homolog Smg or stm3404 or sty4393 or t4100 SWALL:SMG_SALTY (SWALL:Q8XFK8) (157 aa) fasta scores: E(): 8.8e-49, 78.34% id in 157 aa; Belongs to the Smg family.
       0.711
smf
Conserved hypothetical protein; Similar to Escherichia coli Smf protein Smf or b3285/b3286 SWALL:SMF_ECOLI (SWALL:P30852) (374 aa) fasta scores: E(): 1.5e-79, 57.75% id in 374 aa, and to Yersinia pestis hypothetical protein ypo0243 ypo0243 or Smf1 or y4024 SWALL:Q8ZJ78 (EMBL:AJ414141) (373 aa) fasta scores: E(): 1.6e-82, 60.32% id in 373 aa.
       0.708
tsx
Nucleoside-specific channel-forming protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri nucleoside-specific channel-forming protein Tsx precursor Tsx or NupA or b0411 or z0512 or ecs0464 or sf0348 SWALL:TSX_ECOLI (SWALL:P22786) (294 aa) fasta scores: E(): 3.1e-92, 73.46% id in 294 aa.
  
     0.687
ECA2852
Conserved hypothetical protein; Similar to Shigella flexneri 2a hypothetical 32.7 kDa protein SWALL:Q9AL39 (EMBL:AF200692) (280 aa) fasta scores: E(): 5.7e-66, 59.55% id in 272 aa, and to Escherichia coli Z1226 protein z1226 SWALL:CAD33792 (EMBL:AJ488511) (281 aa) fasta scores: E(): 8.4e-69, 62.59% id in 270 aa.
  
     0.634
dinI
DNA-damage-inducible protein I; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri DNA-damage-inducible protein I DinI or b1061 or c1328 or z1698 or ecs1439 or sf1067 SWALL:DINI_ECOLI (SWALL:Q47143) (81 aa) fasta scores: E(): 6.5e-18, 64.19% id in 81 aa.
  
     0.592
ECA2377
Similar to Yersinia pestis hypothetical protein ypo1774 or y2534 SWALL:YH74_YERPE (SWALL:Q8ZFE0) (85 aa) fasta scores: E(): 1.1e-10, 53.84% id in 78 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yoah or b1811 or c2216 or z2854 or ecs2520 SWALL:YOAH_ECOLI (SWALL:P76260) (59 aa) fasta scores: E(): 1.7e-10, 67.24% id in 58 aa; Belongs to the UPF0181 family.
  
     0.577
ECA0045
Putative virulence-associated outer membrane protein; Similar to Salmonella typhimurium resistance to complement killing Rck or pslt009 SWALL:Q04817 (EMBL:L08613) (185 aa) fasta scores: E(): 7.9e-27, 44.68% id in 188 aa, and to Salmonella typhimurium virulence membrane protein PagC precursor or stm1246 SWALL:PAGC_SALTY (SWALL:P23988) (185 aa) fasta scores: E(): 3.5e-26, 45.05% id in 182 aa.
  
     0.547
ECA2749
Similar to Salmonella typhi putative sulphatase sty2466 SWALL:Q8Z579 (EMBL:AL627273) (586 aa) fasta scores: E(): 5.5e-146, 60.47% id in 587 aa, and to Shigella flexneri putative sulfatase yejm or sf2275 SWALL:AAN43794 (EMBL:AE015243) (586 aa) fasta scores: E(): 3.6e-143, 59.11% id in 587 aa.
  
     0.543
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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