STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smgConserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri protein Smg or b3284 or sf3316 SWALL:SMG_ECOLI (SWALL:P30853) (157 aa) fasta scores: E(): 6.6e-48, 76.43% id in 157 aa, and to Salmonella typhimurium, and Salmonella typhi Smg protein homolog Smg or stm3404 or sty4393 or t4100 SWALL:SMG_SALTY (SWALL:Q8XFK8) (157 aa) fasta scores: E(): 8.8e-49, 78.34% id in 157 aa; Belongs to the Smg family. (157 aa)    
Predicted Functional Partners:
smf
Conserved hypothetical protein; Similar to Escherichia coli Smf protein Smf or b3285/b3286 SWALL:SMF_ECOLI (SWALL:P30852) (374 aa) fasta scores: E(): 1.5e-79, 57.75% id in 374 aa, and to Yersinia pestis hypothetical protein ypo0243 ypo0243 or Smf1 or y4024 SWALL:Q8ZJ78 (EMBL:AJ414141) (373 aa) fasta scores: E(): 1.6e-82, 60.32% id in 373 aa.
     
 0.807
tsaC
Putative DNA topoisomerase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
     
 0.756
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.712
ECA3994
Similar to Salmonella typhi hypothetical protein yrdb or sty4397 SWALL:Q8Z1W4 (EMBL:AL627282) (85 aa) fasta scores: E(): 1.2e-18, 58.82% id in 85 aa, and to Escherichia coli hypothetical protein yrdb or b3280 SWALL:YRDB_ECOLI (SWALL:P45795) (85 aa) fasta scores: E(): 1.7e-18, 58.02% id in 81 aa.
       0.711
ECA1310
Similar to Yersinia pestis hypothetical protein Ypo2611 SWALL:Q8ZDF7 (EMBL:AJ414153) (160 aa) fasta scores: E(): 3.3e-46, 76.87% id in 160 aa, and to Salmonella typhimurium putative cytoplasmic protein ybel or stm0653 SWALL:Q8ZQZ2 (EMBL:AE008726) (157 aa) fasta scores: E(): 2.3e-42, 71.25% id in 160 aa.
  
     0.696
zapD
Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
  
     0.687
ECA0898
Conserved hypothetical protein; Similar to Salmonella typhimurium putative cytoplasmic protein stm3196 SWALL:Q8ZLY9 (EMBL:AE008847) (119 aa) fasta scores: E(): 1.4e-20, 75.75% id in 99 aa, and to Escherichia coli hypothetical protein yqiC SWALL:YQIC_ECOLI (SWALL:Q46868) (116 aa) fasta scores: E(): 2e-19, 77.66% id in 94 aa.
  
     0.659
ECA4055
Putative exported protein; Similar to Yersinia pestis hypothetical protein ypo0192 or y3973 SWALL:Q8ZJC3 (EMBL:AJ414141) (73 aa) fasta scores: E(): 1.2e-12, 60% id in 65 aa, and to Shigella flexneri orf, conserved hypothetical protein yhev or sf3368 SWALL:AAN44831 (EMBL:AE015345) (66 aa) fasta scores: E(): 4.4e-11, 50% id in 64 aa.
  
     0.657
ECA2373
Outer membrane lipoprotein; Similar to Escherichia coli, and Escherichia coli O6 hypothetical lipoprotein yeay precursor yeay or b1806 or c2210 SWALL:YEAY_ECOLI (SWALL:P76255) (193 aa) fasta scores: E(): 3.6e-38, 57.36% id in 197 aa, and to Salmonella enterica subsp. enterica serovar Typhi Ty2 putative lipoprotein t1058 SWALL:AAO68724 (EMBL:AE016837) (193 aa) fasta scores: E(): 8.2e-38, 57.36% id in 197 aa.
  
     0.612
dedD
Putative membrane protein; Non-essential cell division protein that could be required for efficient cell constriction.
  
     0.612
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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