Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smfConserved hypothetical protein; Similar to Escherichia coli Smf protein Smf or b3285/b3286 SWALL:SMF_ECOLI (SWALL:P30852) (374 aa) fasta scores: E(): 1.5e-79, 57.75% id in 374 aa, and to Yersinia pestis hypothetical protein ypo0243 ypo0243 or Smf1 or y4024 SWALL:Q8ZJ78 (EMBL:AJ414141) (373 aa) fasta scores: E(): 1.6e-82, 60.32% id in 373 aa. (373 aa)    
Predicted Functional Partners:
ECA4133
Similar to Yersinia pestis hypothetical protein ypo0128 ypo0128 or y3906 SWALL:AAM87448 (EMBL:AJ414141) (233 aa) fasta scores: E(): 7.3e-52, 56.22% id in 233 aa, and to Salmonella typhi putative competence protein sty4286 SWALL:Q8Z222 (EMBL:AL627281) (227 aa) fasta scores: E(): 7.7e-46, 53.21% id in 233 aa.
 
 
 0.927
ECA2558
Similar to Yersinia pestis putative membrane protein ypo1394 or y2778 SWALL:Q8ZGB0 (EMBL:AJ414148) (763 aa) fasta scores: E(): 7.2e-161, 50.19% id in 763 aa, and to Salmonella typhi putative competence-related protein sty0984 SWALL:Q8Z802 (EMBL:AL627268) (754 aa) fasta scores: E(): 7.2e-126, 42.52% id in 762 aa.
 
  
 0.888
ECA4230
Probable magnesium-chelatase; Similar to Haemophilus influenzae competence protein ComM or hi1117 SWALL:COMM_HAEIN (SWALL:P45049) (509 aa) fasta scores: E(): 2.2e-110, 64.22% id in 506 aa, and to Yersinia pestis putative magnesium chelatase family protein ypo3902 SWALL:Q8ZAA9 (EMBL:AJ414159) (507 aa) fasta scores: E(): 5e-130, 73.96% id in 507 aa.
 
 
 0.877
smg
Conserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri protein Smg or b3284 or sf3316 SWALL:SMG_ECOLI (SWALL:P30853) (157 aa) fasta scores: E(): 6.6e-48, 76.43% id in 157 aa, and to Salmonella typhimurium, and Salmonella typhi Smg protein homolog Smg or stm3404 or sty4393 or t4100 SWALL:SMG_SALTY (SWALL:Q8XFK8) (157 aa) fasta scores: E(): 8.8e-49, 78.34% id in 157 aa; Belongs to the Smg family.
     
 0.812
tsaC
Putative DNA topoisomerase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
     
 0.767
recA
RecA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.746
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.732
ECA3994
Similar to Salmonella typhi hypothetical protein yrdb or sty4397 SWALL:Q8Z1W4 (EMBL:AL627282) (85 aa) fasta scores: E(): 1.2e-18, 58.82% id in 85 aa, and to Escherichia coli hypothetical protein yrdb or b3280 SWALL:YRDB_ECOLI (SWALL:P45795) (85 aa) fasta scores: E(): 1.7e-18, 58.02% id in 81 aa.
       0.718
outO
Type 4 prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
  
  
 0.703
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
     0.703
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.