STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
dsrFPutative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (119 aa)    
Predicted Functional Partners:
dsrH
Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
 
 0.999
dsrE
Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.
 
 0.999
tusE
Conserved hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD (By similarity).
 
  
 0.827
ECA4042
Similar to Yersinia pestis putative DNA-binding protein ypo0196 or y3978 SWALL:Q8ZJB9 (EMBL:AJ414141) (244 aa) fasta scores: E(): 1.9e-82, 90.41% id in 240 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yheo or b3346 or c4120 or sf3364 SWALL:YHEO_ECOLI (SWALL:P45533) (240 aa) fasta scores: E(): 9.4e-80, 85.83% id in 240 aa.
  
    0.797
nfi
Endonuclease V (pseudogene); 1 probable transmembrane helix predicted for ECA0236 by TMHMM2.0 at aa 102-124.
  
     0.571
rpsL
30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.
       0.533
sprT
Putative metallopeptidase; Similar to Escherichia coli protein SprT or b2944 SWALL:SPRT_ECOLI (SWALL:P39902) (165 aa) fasta scores: E(): 4.5e-43, 68.51% id in 162 aa; Belongs to the SprT family.
  
     0.479
sirA
SirA protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
 
   
 0.465
ECA0197
Similar to Yersinia pestis hypothetical protein ypo3780 SWALL:Q8ZAM0 (EMBL:AJ414158) (210 aa) fasta scores: E(): 1.8e-42, 56.65% id in 203 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein YigP SWALL:YIGP_ECOLI (SWALL:P27852) (201 aa) fasta scores: E(): 1.2e-35, 48.78% id in 205 aa.
  
   
 0.460
seqA
Putative negative regulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.426
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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