node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ECA0197 | dsrF | ECA0197 | ECA4040 | Similar to Yersinia pestis hypothetical protein ypo3780 SWALL:Q8ZAM0 (EMBL:AJ414158) (210 aa) fasta scores: E(): 1.8e-42, 56.65% id in 203 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein YigP SWALL:YIGP_ECOLI (SWALL:P27852) (201 aa) fasta scores: E(): 1.2e-35, 48.78% id in 205 aa. | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 0.460 |
ECA0197 | seqA | ECA0197 | ECA1335 | Similar to Yersinia pestis hypothetical protein ypo3780 SWALL:Q8ZAM0 (EMBL:AJ414158) (210 aa) fasta scores: E(): 1.8e-42, 56.65% id in 203 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein YigP SWALL:YIGP_ECOLI (SWALL:P27852) (201 aa) fasta scores: E(): 1.2e-35, 48.78% id in 205 aa. | Putative negative regulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.519 |
ECA4042 | dsrE | ECA4042 | ECA4041 | Similar to Yersinia pestis putative DNA-binding protein ypo0196 or y3978 SWALL:Q8ZJB9 (EMBL:AJ414141) (244 aa) fasta scores: E(): 1.9e-82, 90.41% id in 240 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yheo or b3346 or c4120 or sf3364 SWALL:YHEO_ECOLI (SWALL:P45533) (240 aa) fasta scores: E(): 9.4e-80, 85.83% id in 240 aa. | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | 0.807 |
ECA4042 | dsrF | ECA4042 | ECA4040 | Similar to Yersinia pestis putative DNA-binding protein ypo0196 or y3978 SWALL:Q8ZJB9 (EMBL:AJ414141) (244 aa) fasta scores: E(): 1.9e-82, 90.41% id in 240 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yheo or b3346 or c4120 or sf3364 SWALL:YHEO_ECOLI (SWALL:P45533) (240 aa) fasta scores: E(): 9.4e-80, 85.83% id in 240 aa. | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 0.797 |
ECA4042 | dsrH | ECA4042 | ECA4039 | Similar to Yersinia pestis putative DNA-binding protein ypo0196 or y3978 SWALL:Q8ZJB9 (EMBL:AJ414141) (244 aa) fasta scores: E(): 1.9e-82, 90.41% id in 240 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yheo or b3346 or c4120 or sf3364 SWALL:YHEO_ECOLI (SWALL:P45533) (240 aa) fasta scores: E(): 9.4e-80, 85.83% id in 240 aa. | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 0.748 |
ECA4042 | rpsL | ECA4042 | ECA4038 | Similar to Yersinia pestis putative DNA-binding protein ypo0196 or y3978 SWALL:Q8ZJB9 (EMBL:AJ414141) (244 aa) fasta scores: E(): 1.9e-82, 90.41% id in 240 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yheo or b3346 or c4120 or sf3364 SWALL:YHEO_ECOLI (SWALL:P45533) (240 aa) fasta scores: E(): 9.4e-80, 85.83% id in 240 aa. | 30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.503 |
dsrE | ECA4042 | ECA4041 | ECA4042 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | Similar to Yersinia pestis putative DNA-binding protein ypo0196 or y3978 SWALL:Q8ZJB9 (EMBL:AJ414141) (244 aa) fasta scores: E(): 1.9e-82, 90.41% id in 240 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yheo or b3346 or c4120 or sf3364 SWALL:YHEO_ECOLI (SWALL:P45533) (240 aa) fasta scores: E(): 9.4e-80, 85.83% id in 240 aa. | 0.807 |
dsrE | dsrF | ECA4041 | ECA4040 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 0.999 |
dsrE | dsrH | ECA4041 | ECA4039 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 0.995 |
dsrE | rpsL | ECA4041 | ECA4038 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | 30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.533 |
dsrE | sirA | ECA4041 | ECA4353 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | SirA protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. | 0.982 |
dsrE | sprT | ECA4041 | ECA3921 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | Putative metallopeptidase; Similar to Escherichia coli protein SprT or b2944 SWALL:SPRT_ECOLI (SWALL:P39902) (165 aa) fasta scores: E(): 4.5e-43, 68.51% id in 162 aa; Belongs to the SprT family. | 0.439 |
dsrE | tusE | ECA4041 | ECA1762 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | Conserved hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD (By similarity). | 0.985 |
dsrF | ECA0197 | ECA4040 | ECA0197 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | Similar to Yersinia pestis hypothetical protein ypo3780 SWALL:Q8ZAM0 (EMBL:AJ414158) (210 aa) fasta scores: E(): 1.8e-42, 56.65% id in 203 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein YigP SWALL:YIGP_ECOLI (SWALL:P27852) (201 aa) fasta scores: E(): 1.2e-35, 48.78% id in 205 aa. | 0.460 |
dsrF | ECA4042 | ECA4040 | ECA4042 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | Similar to Yersinia pestis putative DNA-binding protein ypo0196 or y3978 SWALL:Q8ZJB9 (EMBL:AJ414141) (244 aa) fasta scores: E(): 1.9e-82, 90.41% id in 240 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein yheo or b3346 or c4120 or sf3364 SWALL:YHEO_ECOLI (SWALL:P45533) (240 aa) fasta scores: E(): 9.4e-80, 85.83% id in 240 aa. | 0.797 |
dsrF | dsrE | ECA4040 | ECA4041 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. | 0.999 |
dsrF | dsrH | ECA4040 | ECA4039 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 0.999 |
dsrF | nfi | ECA4040 | ECA0237 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | Endonuclease V (pseudogene); 1 probable transmembrane helix predicted for ECA0236 by TMHMM2.0 at aa 102-124. | 0.571 |
dsrF | rpsL | ECA4040 | ECA4038 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | 30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.533 |
dsrF | seqA | ECA4040 | ECA1335 | Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. | Putative negative regulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.426 |