STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pmrATwo-component response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum response regulator PmrA SWALL:CAE47079 (EMBL:AJ583007) (222 aa) fasta scores: E(): 6.4e-85, 98.19% id in 222 aa, and to Escherichia coli transcriptional regulatory protein BasR or PmrA or b4113 SWALL:BASR_ECOLI (SWALL:P30843) (222 aa) fasta scores: E(): 1.4e-52, 60.63% id in 221 aa. (222 aa)    
Predicted Functional Partners:
pmrB
Two-component sensor kinase; Similar to Pectobacterium carotovorum subsp. carotovorum sensor kinase PmrB SWALL:CAE47080 (EMBL:AJ583007) (364 aa) fasta scores: E(): 1.5e-125, 94.78% id in 364 aa, and to Escherichia coli sensor protein BasS or PmrB or b4112 SWALL:BASS_ECOLI (SWALL:P30844) (363 aa) fasta scores: E(): 9.5e-69, 58.64% id in 353 aa.
 
 0.998
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
0.951
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
 
 0.940
ECA0786
Two component system sensor kinase; Similar to Pseudomonas putida sensor histidine kinase pp2906 SWALL:AAN68514 (EMBL:AE016784) (463 aa) fasta scores: E(): 2.3e-32, 30.91% id in 427 aa, and to Rhizobium loti sensory histidine protein kinase mlr4459 SWALL:Q98E08 (EMBL:AP003004) (458 aa) fasta scores: E(): 1.2e-30, 31.25% id in 464 aa.
 
 0.860
qseC
Two-component system sensor kinase; Similar to Escherichia coli sensor protein QseC SWALL:QSEC_ECOLI (SWALL:P40719) (449 aa) fasta scores: E(): 7.4e-94, 56.15% id in 447 aa.
 
 
 0.856
rcsC
Two-component system sensor protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
 
 0.809
cpxA
Two-component sensor kinase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 sensor protein CpxA or EcfB or Ssd or Eup or b3911 or c4863 or z5456 or ecs4837 SWALL:CPXA_ECOLI (SWALL:P08336) (457 aa) fasta scores: E(): 1.8e-151, 80.04% id in 456 aa.
 
 0.802
pmrC
Putative sulfatase; Similar to Pectobacterium carotovorum subsp. carotovorum putative cytoplasmic membrane protein PmrC pmrC SWALL:CAE47078 (EMBL:AJ583007) (548 aa) fasta scores: E(): 4.1e-202, 93.79% id in 548 aa, and to Escherichia coli hypothetical protein yjdb or b4114 SWALL:YJDB_ECOLI (SWALL:P30845) (547 aa) fasta scores: E(): 1.2e-128, 59.29% id in 538 aa.
  
  
 0.801
ECA0890
Two-component system sensor kinase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 sensor protein CpxA or EcfB or Ssd or Eup or b3911 or c4863 or z5456 or ecs4837 SWALL:CPXA_ECOLI (SWALL:P08336) (457 aa) fasta scores: E(): 2.2e-23, 29.53% id in 474 aa, and to Yersinia pestis putative two-component system sensor kinase ypo2997 or y1483 SWALL:Q8ZCJ0 (EMBL:AJ414154) (449 aa) fasta scores: E(): 1e-91, 56.86% id in 459 aa.
 
 
 0.791
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
 
 
 0.791
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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