STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pmrBTwo-component sensor kinase; Similar to Pectobacterium carotovorum subsp. carotovorum sensor kinase PmrB SWALL:CAE47080 (EMBL:AJ583007) (364 aa) fasta scores: E(): 1.5e-125, 94.78% id in 364 aa, and to Escherichia coli sensor protein BasS or PmrB or b4112 SWALL:BASS_ECOLI (SWALL:P30844) (363 aa) fasta scores: E(): 9.5e-69, 58.64% id in 353 aa. (364 aa)    
Predicted Functional Partners:
pmrA
Two-component response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum response regulator PmrA SWALL:CAE47079 (EMBL:AJ583007) (222 aa) fasta scores: E(): 6.4e-85, 98.19% id in 222 aa, and to Escherichia coli transcriptional regulatory protein BasR or PmrA or b4113 SWALL:BASR_ECOLI (SWALL:P30843) (222 aa) fasta scores: E(): 1.4e-52, 60.63% id in 221 aa.
 
 0.998
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
 0.988
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
0.944
pehR
Two-component response regulator of virulence determinants; Similar to Pectobacterium carotovorum subsp. carotovorum response regulator PehR SWALL:Q9ZIN9 (EMBL:AF022772) (227 aa) fasta scores: E(): 1.5e-76, 91.26% id in 229 aa, and to Erwinia chrysanthemi PhoP protein phoP SWALL:CAD33237 (EMBL:AJ489252) (222 aa) fasta scores: E(): 7.2e-74, 87.83% id in 222 aa.
 
 0.922
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
0.908
qseB
Two-component system response regulator; Similar to Escherichia coli transcriptional regulatory protein QseB SWALL:QSEB_ECOLI (SWALL:P52076) (219 aa) fasta scores: E(): 3.1e-59, 68.34% id in 218 aa.
 
 0.888
pmrC
Putative sulfatase; Similar to Pectobacterium carotovorum subsp. carotovorum putative cytoplasmic membrane protein PmrC pmrC SWALL:CAE47078 (EMBL:AJ583007) (548 aa) fasta scores: E(): 4.1e-202, 93.79% id in 548 aa, and to Escherichia coli hypothetical protein yjdb or b4114 SWALL:YJDB_ECOLI (SWALL:P30845) (547 aa) fasta scores: E(): 1.2e-128, 59.29% id in 538 aa.
  
  
 0.848
cpxR
Two-component response regulator; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulatory protein CpxR or b3912 or z5457 or ecs4838 or sf3991 SWALL:CPXR_ECOLI (SWALL:P16244) (232 aa) fasta scores: E(): 5.3e-78, 88.79% id in 232 aa.
 
 0.846
ECA0785
Two component system response regulator; Similar to Alcaligenes eutrophus transcriptional activator protein CzcR czcR SWALL:CZCR_ALCEU (SWALL:Q44006) (225 aa) fasta scores: E(): 8.9e-30, 42.15% id in 223 aa, and to Brucella suis DNA-binding response regulator br0612 SWALL:AAN29541 (EMBL:AE014368) (235 aa) fasta scores: E(): 5.5e-33, 43.27% id in 238 aa.
 
 0.842
baeR
Two-component system response regulator; Similar to Escherichia coli, and Escherichia coli O6 transcriptional regulatory protein BaeR baer or b2079 or c2605 SWALL:BAER_ECOLI (SWALL:P30846) (240 aa) fasta scores: E(): 5.7e-63, 73.12% id in 227 aa.
 
 0.830
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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