STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fkpASimilar to Escherichia coli fkbp-type peptidyl-prolyl cis-trans isomerase FkpA precursor FkpA or b3347 SWALL:FKBA_ECOLI (SWALL:P45523) (270 aa) fasta scores: E(): 9.4e-63, 73.13% id in 268 aa. (272 aa)    
Predicted Functional Partners:
htpG
Chaperone protein; Molecular chaperone. Has ATPase activity.
   
 0.847
degP
Protease Do; Similar to Escherichia coli, and Escherichia coli O157:H7 protease Do precursor DegP or HtrA or Ptd or b0161 or z0173 or ecs0165 SWALL:DEGP_ECOLI (SWALL:P09376) (474 aa) fasta scores: E(): 1.3e-102, 70.28% id in 488 aa; Belongs to the peptidase S1C family.
   
 
 0.681
degQ
Exported protease; Similar to Escherichia coli protease degq precursor degq or hhoa or b3234 SWALL:DEGQ_ECOLI (SWALL:P39099) (455 aa) fasta scores: E(): 9.7e-110, 70.67% id in 457 aa; Belongs to the peptidase S1C family.
   
 
 0.676
ECA0531
PS00736 Single-strand binding protein family signature 2.
    
 
 0.634
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
 
 0.634
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.627
ecfK
Putative surface antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
   
 
 0.619
ompH
Outer membrane protein; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
   
  
 0.608
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 
 0.606
surA
Survival protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
   
 
 0.605
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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