Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA4051Putative transcriptional regulator; Similar to Xanthomonas campestris hypothetical protein Xcc0062 SWALL:Q8PEB9 (EMBL:AE012100) (116 aa) fasta scores: E(): 3.8e-29, 75.47% id in 106 aa, and to Rhizobium loti hypothetical protein Mll3985 SWALL:Q98F15 (EMBL:AP003003) (137 aa) fasta scores: E(): 3.7e-28, 76.47% id in 102 aa. (121 aa)    
Predicted Functional Partners:
ECA2235
Putative transcriptional regulator; Similar to Pseudomonas putida conserved hypothetical protein pp2987 SWALL:AAN68595 (EMBL:AE016785) (187 aa) fasta scores: E(): 2.1e-33, 70.24% id in 121 aa, and to Rhizobium loti hypothetical protein Mll2592 SWALL:Q98I32 (EMBL:AP003000) (182 aa) fasta scores: E(): 6.4e-17, 49.56% id in 115 aa.
  
     0.607
ECA4052
Similar to Rhizobium loti hypothetical protein Mlr3986 SWALL:Q98F14 (EMBL:AP003003) (109 aa) fasta scores: E(): 1.3e-15, 47.22% id in 108 aa, and to Agrobacterium tumefaciens hypothetical protein atu5209 or agr_pat_291 SWALL:Q8UKB4 (EMBL:AE008943) (109 aa) fasta scores: E(): 1.4e-12, 40.18% id in 107 aa.
       0.554
ECA4053
Putative short chain dehydrogenase; Similar to Agrobacterium tumefaciens dehydrogenase atu5210 or agr_pat_293 SWALL:Q8UKB3 (EMBL:AE008943) (259 aa) fasta scores: E(): 9.5e-62, 65.11% id in 258 aa, and to Rhizobium meliloti sma1629 protein ra0888 or sma1629 SWALL:Q92YJ2 (EMBL:AE007275) (259 aa) fasta scores: E(): 1.4e-64, 70.86% id in 254 aa.
       0.548
ECA0348
GntR-family transcriptional regulator; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical transcriptional regulator YegW SWALL:YEGW_ECOLI (SWALL:P76420) (248 aa) fasta scores: E(): 3.2e-22, 30.8% id in 237 aa.
   
  
 0.539
nadR
Similar to Salmonella typhimurium transcriptional regulator NadR SWALL:NADR_SALTY (SWALL:P24518) (410 aa) fasta scores: E(): 1.1e-140, 85.5% id in 407 aa, and to Escherichia coli transcriptional regulator NadR or NadI or b4390 SWALL:NADR_ECOLI (SWALL:P27278) (410 aa) fasta scores: E(): 2.2e-139, 83.9% id in 410 aa.
   
    0.534
pspC
Phage shock protein C; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri phage shock protein C PspC or b1306 or c1777 or z2479 or ecs1883 or sf1311 SWALL:PSPC_ECOLI (SWALL:P23855) (119 aa) fasta scores: E(): 1.5e-25, 63.15% id in 114 aa.
   
  
 0.433
ECA1566
Putative membrane protein; Similar to Ralstonia solanacearum probable transmembrane protein rsc0603 or rs04842 SWALL:Q8Y1T6 (EMBL:AL646060) (292 aa) fasta scores: E(): 4.1e-18, 32.27% id in 189 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri paraquat-inducible protein a pqia or pqi5a or b0950 or c1086 or sf0951 SWALL:PQIA_ECOLI (SWALL:P43670) (417 aa) fasta scores: E(): 3.4e-07, 23.4% id in 188 aa.
   
  
 0.423
ECA0443
Conserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri hypothetical protein YoeB SWALL:YOEB_ECOLI (SWALL:P56605) (84 aa) fasta scores: E(): 8.2e-31, 85.71% id in 84 aa.
      
 0.415
nuoN
NADH-quinone oxidoreductase chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
      
 0.415
nuoA
NADH-quinone oxidoreductase chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.
      
 0.415
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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