STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crpCyclic AMP receptor protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri catabolite gene activator Crp or Cap or Csm or b3357 or c4132 or z4718 or ecs4208 or sf3376 SWALL:CRP_ECOLI (SWALL:P03020) (210 aa) fasta scores: E(): 6.2e-78, 99.04% id in 210 aa, and to Pectobacterium carotovorum subsp. carotovorum CrP SWALL:Q8KJ23 (EMBL:AB090359) (210 aa) fasta scores: E(): 4.6e-78, 99.04% id in 210 aa, and to Erwinia chrysanthemi Crp regulatory protein CrP SWALL:O07097 (EMBL:X89443) (210 aa) fasta scores: E(): 7.2e-77, 97.14% id in 210 aa. (210 aa)    
Predicted Functional Partners:
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
    
 0.971
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
 0.968
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.945
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.936
cyaA
Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family.
  
  
 0.927
rpoB
DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.882
rpoC
DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.882
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.871
ECA2142
Urea amidolyase; Similar to the C-terminal region of Saccharomyces cerevisiae urea amidolyase [includes: urea carboxylase and allophanate hydrolase] Dur1,2 or ybr208c or ybr1448 SWALL:DUR1_YEAST (SWALL:P32528) (1835 aa) fasta scores: E(): 0, 52.92% id in 1213 aa, and to Pseudomonas fluorescens urea amidolyase homologue uahA SWALL:Q9XAV3 (EMBL:AJ243652) (1213 aa) fasta scores: E(): 0, 51.47% id in 1224 aa.
    
  0.817
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.810
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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