STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpeRibulose-phosphate 3-epimerase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribulose-phosphate 3-epimerase Rpe or Dod or b3386 or c4156 or z4739 or ecs4228 or sf3404 SWALL:RPE_ECOLI (SWALL:P32661) (225 aa) fasta scores: E(): 5.1e-71, 83.92% id in 224 aa. (225 aa)    
Predicted Functional Partners:
ECA1950
Similar to the N-terminal region of Homo sapiens transketolase Tkt or Tkt1 SWALL:TKT_HUMAN (SWALL:P29401) (623 aa) fasta scores: E(): 1.8e-21, 34.22% id in 263 aa, and to Yersinia pestis putative N-terminal region of transketolase ypo3314 SWALL:Q8ZBT1 (EMBL:AJ414156) (276 aa) fasta scores: E(): 3e-96, 88.4% id in 276 aa.
  
 0.991
tktA1
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
 0.969
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 0.953
gnd
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 0.946
ECA1951
Putative transketolase C-terminal section; Similar to Escherichia coli 1-deoxy-D-xylulose 5-phosphate synthase Dxs or b0420 SWALL:DXS_ECOLI (SWALL:P77488) (619 aa) fasta scores: E(): 7.6e-18, 30.24% id in 281 aa, and to Yersinia pestis c-terminal region of transketolase ypo3313 SWALL:Q8ZBT2 (EMBL:AJ414156) (314 aa) fasta scores: E(): 2e-97, 80.19% id in 313 aa.
  
 
 0.931
rpiB
Ribose 5-phosphate isomerase; Involved in catabolism of D-apiose. Catalyzes the isomerization of D-erythrulose 4-phosphate to D-erythrose 4-phosphate.
  
 
 0.929
xylB
Xylulose kinase; Similar to Escherichia coli xylulose kinase XylB SWALL:XYLB_ECOLI (SWALL:P09099) (484 aa) fasta scores: E(): 7.7e-141, 73.81% id in 485 aa.
 
  
 0.928
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.916
araD
Similar to Escherichia coli L-ribulose-5-phosphate 4-epimerase AraD or b0061 SWALL:ARAD_ECOLI (SWALL:P08203) (231 aa) fasta scores: E(): 5.3e-74, 77.48% id in 231 aa.
     
 0.909
araB
L-ribulokinase; Similar to Escherichia coli L-ribulokinase AraB or b0063 SWALL:ARAB_ECOLI (SWALL:P08204) (565 aa) fasta scores: E(): 7.7e-174, 71.79% id in 553 aa.
   
 0.908
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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