Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nudESimilar to Escherichia coli ADP compounds hydrolase NudE or b3397 SWALL:NUDE_ECOLI (SWALL:P45799) (186 aa) fasta scores: E(): 2.1e-54, 76.75% id in 185 aa. (185 aa)    
Predicted Functional Partners:
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
    
  0.946
pgm
Phosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm or b0688 SWALL:PGMU_ECOLI (SWALL:P36938) (546 aa) fasta scores: E(): 5e-188, 87.72% id in 546 aa.
   
 
  0.945
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.945
nudF
ADP-ribose pyrophosphatase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ADP-ribose pyrophosphatase NudF or b3034 or c3780 or z4391 or ecs3922 or sf3074 SWALL:ADPP_ECOLI (SWALL:P36651) (209 aa) fasta scores: E(): 8.2e-61, 79.1% id in 201 aa.
     
  0.944
ECA4101
Similar to Yersinia pestis hypothetical protein Ypo0143 SWALL:Q8ZJG5 (EMBL:AJ414141) (64 aa) fasta scores: E(): 0.17, 36.17% id in 47 aa.
       0.737
nnrE
Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
 
 0.618
cueR
Copper efflux regulator; Similar to Escherichia coli, and Shigella flexneri transcriptional regulator CueR or b0487 or sf0432 SWALL:CUER_ECOLI (SWALL:P77565) (135 aa) fasta scores: E(): 8.4e-34, 72.51% id in 131 aa.
   
    0.554
ECA1575
Similar to Rhizobium leguminosarum transcriptional regulator HmrR SWALL:HMMR_RHILV (SWALL:Q9X5V4) (129 aa) fasta scores: E(): 3.2e-07, 33.6% id in 125 aa, and to Pseudomonas aeruginosa probable transcriptional regulator pa5116 SWALL:Q9HU68 (EMBL:AE004924) (141 aa) fasta scores: E(): 1.4e-21, 54.03% id in 124 aa.
   
    0.554
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
   
    0.553
igaA
Similar to Salmonella typhimurium intracellular growth attenuator protein IgaA or stm3495 SWALL:IGAA_SALTY (SWALL:Q9ACP0) (710 aa) fasta scores: E(): 2.3e-132, 50.14% id in 716 aa, and to Proteus mirabilis flagellar operon control protein UmoB SWALL:UMOB_PROMI (SWALL:O86988) (702 aa) fasta scores: E(): 1.8e-100, 40.11% id in 698 aa.
     
 0.525
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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