STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
envZSimilar to Salmonella typhi osmolarity sensor protein envz envz or sty4295 or t4005 SWALL:ENVZ_SALTI (SWALL:P41406) (450 aa) fasta scores: E(): 2.2e-144, 84.1% id in 434 aa. (452 aa)    
Predicted Functional Partners:
ompR
Two-component osmolarity response regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, Salmonella typhimurium, Salmonella typhi, and Shigella flexneri transcriptional regulatory protein OmpR or OmpB or Kmt or b3405 or c4181 or z4760 or ecs4247 or stm3502 or sty4294 or t4004 or sf3424 SWALL:OMPR_ECOLI (SWALL:P03025) (239 aa) fasta scores: E(): 3.6e-91, 99.16% id in 239 aa.
 
 0.999
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
 0.988
mzrA
Putative exported protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
 
 0.985
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
0.933
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
0.911
cpxR
Two-component response regulator; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulatory protein CpxR or b3912 or z5457 or ecs4838 or sf3991 SWALL:CPXR_ECOLI (SWALL:P16244) (232 aa) fasta scores: E(): 5.3e-78, 88.79% id in 232 aa.
 
 0.898
pehR
Two-component response regulator of virulence determinants; Similar to Pectobacterium carotovorum subsp. carotovorum response regulator PehR SWALL:Q9ZIN9 (EMBL:AF022772) (227 aa) fasta scores: E(): 1.5e-76, 91.26% id in 229 aa, and to Erwinia chrysanthemi PhoP protein phoP SWALL:CAD33237 (EMBL:AJ489252) (222 aa) fasta scores: E(): 7.2e-74, 87.83% id in 222 aa.
 
 0.875
baeR
Two-component system response regulator; Similar to Escherichia coli, and Escherichia coli O6 transcriptional regulatory protein BaeR baer or b2079 or c2605 SWALL:BAER_ECOLI (SWALL:P30846) (240 aa) fasta scores: E(): 5.7e-63, 73.12% id in 227 aa.
 
 0.841
arcA
Aerobic respiration control protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri aerobic respiration control protein ArcA or Dye or FexA or SfrA or Seg or Msp or CpxC or b4401 or c5488 or z6004 or ecs5359 or sf4433 SWALL:ARCA_ECOLI (SWALL:P03026) (238 aa) fasta scores: E(): 6.2e-85, 94.11% id in 238 aa.
 
 0.819
qseB
Two-component system response regulator; Similar to Escherichia coli transcriptional regulatory protein QseB SWALL:QSEB_ECOLI (SWALL:P52076) (219 aa) fasta scores: E(): 3.1e-59, 68.34% id in 218 aa.
 
 0.802
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.