STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
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[Homology]
Score
kdgT2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system. Belongs to the KdgT transporter family. (318 aa)    
Predicted Functional Partners:
kduI2
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
     
 0.941
ogl
Oligogalacturonate lyase; Involved in degradation of pectin, which causes soft-rod disease in plants.
      
 0.774
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
      
 0.774
kduI1
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
     
 0.745
rhiE
Rhamnogalacturonate lyase; Similar to Erwinia chrysanthemi rhamnogalacturonase precursor RhiE SWALL:Q8RJP2 (EMBL:AJ438339) (578 aa) fasta scores: E(): 1.3e-133, 60.1% id in 554 aa. The only other significant database matches are of eukaryotic origin.
      
 0.736
kdgK
2-dehydro-3-deoxygluconokinase; Similar to Erwinia chrysanthemi 2-dehydro-3-deoxygluconokinase KdgK SWALL:KDGK_ERWCH (SWALL:P45416) (310 aa) fasta scores: E(): 1.4e-100, 82.25% id in 310 aa.
  
  
 0.654
dtnK
Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of D-threonate to D-threonate 4-phosphate. Can also phosphorylate 4-hydroxy-L-threonine, with lower efficiency.
 
   
 0.620
eda
Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri Khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase and 2- dehydro-3-deoxyphosphogluconate aldolase Eda or Hga or KdgA or b1850 or c2263 or z2902 or ecs2560 or sf1860 SWALL:ALKH_ECOLI (SWALL:P10177) (213 aa) fasta scores: E(): 1.2e-67, 89.15% id in 212 aa, and to Erwinia chrysanthemi khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase Eda or KdgA SWALL:ALKH_ERWCH (SWALL:P38448) (213 aa) fasta scores: E(): 7e-67, 89.2% id in 213 aa.
  
  
 0.616
dgoA2
Similar to the N-terminal region of Escherichia coli DgoA protein [includes: 2-dehydro-3-deoxyphosphogalactonate aldolase; galactonate dehydratase] DgoA or DgoD or b3692 SWALL:DGOA_ECOLI (SWALL:P31458) (587 aa) fasta scores: E(): 1.3e-38, 61.08% id in 203 aa, and similar, over the entire length, to Xanthomonas axonopodis 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase DgoA or xac1766 SWALL:Q8PLM9 (EMBL:AE011808) (210 aa) fasta scores: E(): 2.8e-38, 56.63% id in 196 aa.
  
  
 0.614
RhiT
Similar to Erwinia chrysanthemi oligogalacturonide transporter TogT SWALL:Q93KC2 (EMBL:AJ305143) (508 aa) fasta scores: E(): 1.2e-83, 42% id in 519 aa. Also similar to ECA0817 (TogT) (40.426% id. in 517 aa overlap).
  
   
 0.558
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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