STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kduI24-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (278 aa)    
Predicted Functional Partners:
kduD
2-keto-3-deoxygluconate oxidoreductase; Similar to Pectobacterium carotovorum subsp. atrosepticum 2-keto-3-deoxygluconate oxidoreductase KduD SWALL:Q8KHI5 (EMBL:AJ506783) (253 aa) fasta scores: E(): 6.3e-94, 98.41% id in 253 aa, and to Erwinia chrysanthemi 2-deoxy-D-gluconate 3-dehydrogenase KduD SWALL:KDUD_ERWCH (SWALL:Q05528) (253 aa) fasta scores: E(): 4.4e-87, 89.72% id in 253 aa.
 
 
 0.988
ogl
Oligogalacturonate lyase; Involved in degradation of pectin, which causes soft-rod disease in plants.
     
 0.946
kduI1
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
  
  
 
0.901
kdgT
2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system. Belongs to the KdgT transporter family.
     
 0.887
uxaC
Uronate isomerase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri uronate isomerase UxaC or b3092 or c3850 or sf3132 SWALL:UXAC_ECOLI (SWALL:P42607) (470 aa) fasta scores: E(): 8.6e-183, 89.33% id in 469 aa.
 
  
 0.796
pehN
Similar to Erwinia chrysanthemi putative polygalacturonase precursor PehN SWALL:Q8KKH7 (EMBL:AJ292044) (457 aa) fasta scores: E(): 9.4e-151, 80.13% id in 458 aa; Belongs to the glycosyl hydrolase 28 family.
 
     0.699
uxaA
Similar to Escherichia coli altronate hydrolase UxaA SWALL:UXAA_ECOLI (SWALL:P42604) (495 aa) fasta scores: E(): 4.1e-163, 80.24% id in 496 aa.
 
  
 0.686
ECA3749
Similar to Erwinia chrysanthemi RhiN protein RhiN SWALL:CAC83616 (EMBL:AJ292045) (379 aa) fasta scores: E(): 1.8e-53, 45.01% id in 311 aa, and to Agrobacterium tumefaciens hypothetical protein atu4561 atu4561 or agr_l_618 SWALL:Q8U793 (EMBL:AE009384) (397 aa) fasta scores: E(): 4.9e-74, 53.46% id in 361 aa. Also similar to ECA3559 (RhiN) (43.810% id. in 315 aa overlap).
 
   
 0.684
pehX
Similar to Erwinia chrysanthemi exo-poly-alpha-D-galacturonosidase precursor PehX SWALL:PEHX_ERWCH (SWALL:P15922) (602 aa) fasta scores: E(): 1e-59, 48.5% id in 635 aa, and to Klebsiella oxytoca polygalacturonase PehX SWALL:Q8VP71 (EMBL:AY065648) (658 aa) fasta scores: E(): 2.7e-155, 60.63% id in 658 aa; Belongs to the glycosyl hydrolase 28 family.
 
     0.674
uxaB1
Altronate oxidoreductase; Similar to Escherichia coli, and Escherichia coli O157:H7 altronate oxidoreductase UxaB or b1521 or z2184 or ecs2128 SWALL:UXAB_ECOLI (SWALL:P24214) (483 aa) fasta scores: E(): 2e-148, 72.54% id in 488 aa, and to Yersinia pestis altronate oxidoreductase UxaB SWALL:AAM87147 (EMBL:AJ414143) (483 aa) fasta scores: E(): 3e-163, 80.28% id in 487 aa. Also similar to ECA4383 (69.278% id. in 485 aa overlap); Belongs to the mannitol dehydrogenase family. UxaB subfamily.
 
   
 0.666
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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