STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4130Alkaline phosphatase; Similar to Schizophyllum commune alkaline phosphatase Pho1 SWALL:Q9UR10 (EMBL:AF209194) (604 aa) fasta scores: E(): 5.3e-20, 32.91% id in 477 aa, and to Schizosaccharomyces pombe alkaline phosphatase spbc14f5.13C SWALL:PPB_SCHPO (SWALL:O60109) (532 aa) fasta scores: E(): 8.8e-15, 26.68% id in 491 aa. (581 aa)    
Predicted Functional Partners:
ECA4129
Putative exported protein; Similar to Deinococcus radiodurans hypothetical protein Drb0048 SWALL:Q9RZR7 (EMBL:AE001826) (152 aa) fasta scores: E(): 9.8e-20, 48.36% id in 122 aa.
 
     0.946
ECA4127
Putative permease; Similar to Pseudomonas putida ABC efflux transporter, permease protein, putative pp0506 SWALL:AAN66134 (EMBL:AE016775) (421 aa) fasta scores: E(): 3.1e-13, 30.02% id in 423 aa, and to Vibrio cholerae hypothetical protein Vc2554 SWALL:Q9KP25 (EMBL:AE004324) (421 aa) fasta scores: E(): 2.7e-10, 27.86% id in 427 aa.
 
     0.935
nudB
DATP pyrophosphohydrolase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri DATP pyrophosphohydrolase NudB or NtpA or b1865 or z2917 or ecs2575 or sf1875 SWALL:NUDB_ECOLI (SWALL:P24236) (150 aa) fasta scores: E(): 7e-46, 76.02% id in 146 aa.
     
 0.904
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
  0.901
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
     
  0.900
folE
GTP cyclohydrolase I; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri GTP cyclohydrolase I FolE or b2153 or c2688 or z3409 or ecs3045 or sf2238 SWALL:GCH1_ECOLI (SWALL:P27511) (221 aa) fasta scores: E(): 9.1e-71, 88.18% id in 220 aa.
   
 
  0.900
folX
D-erythro-7,8-dihydroneopterin triphosphate epimerase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri D-erythro-7,8-dihydroneopterin triphosphate epimerase FolX or b2303 or c2846 or z3565 or ecs3187 or sf2379 SWALL:FOLX_ECOLI (SWALL:P80449) (119 aa) fasta scores: E(): 1.1e-32, 77.39% id in 115 aa.
     
  0.900
ECA3553
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri putative 6-pyruvoyl tetrahydrobiopterin synthase YgcM or b2765 or z4075 or ecs3620 or sf2781 SWALL:PTPS_ECOLI (SWALL:Q46903) (121 aa) fasta scores: E(): 8.1e-44, 86.66% id in 120 aa.
     
  0.900
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
  0.900
rsgA
Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
     
  0.900
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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