STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4133Similar to Yersinia pestis hypothetical protein ypo0128 ypo0128 or y3906 SWALL:AAM87448 (EMBL:AJ414141) (233 aa) fasta scores: E(): 7.3e-52, 56.22% id in 233 aa, and to Salmonella typhi putative competence protein sty4286 SWALL:Q8Z222 (EMBL:AL627281) (227 aa) fasta scores: E(): 7.7e-46, 53.21% id in 233 aa. (233 aa)    
Predicted Functional Partners:
smf
Conserved hypothetical protein; Similar to Escherichia coli Smf protein Smf or b3285/b3286 SWALL:SMF_ECOLI (SWALL:P30852) (374 aa) fasta scores: E(): 1.5e-79, 57.75% id in 374 aa, and to Yersinia pestis hypothetical protein ypo0243 ypo0243 or Smf1 or y4024 SWALL:Q8ZJ78 (EMBL:AJ414141) (373 aa) fasta scores: E(): 1.6e-82, 60.32% id in 373 aa.
 
 
 0.920
ECA2558
Similar to Yersinia pestis putative membrane protein ypo1394 or y2778 SWALL:Q8ZGB0 (EMBL:AJ414148) (763 aa) fasta scores: E(): 7.2e-161, 50.19% id in 763 aa, and to Salmonella typhi putative competence-related protein sty0984 SWALL:Q8Z802 (EMBL:AL627268) (754 aa) fasta scores: E(): 7.2e-126, 42.52% id in 762 aa.
 
  
 0.857
ECA4230
Probable magnesium-chelatase; Similar to Haemophilus influenzae competence protein ComM or hi1117 SWALL:COMM_HAEIN (SWALL:P45049) (509 aa) fasta scores: E(): 2.2e-110, 64.22% id in 506 aa, and to Yersinia pestis putative magnesium chelatase family protein ypo3902 SWALL:Q8ZAA9 (EMBL:AJ414159) (507 aa) fasta scores: E(): 5e-130, 73.96% id in 507 aa.
 
  
 0.845
tyrA
Similar to Escherichia coli T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA or b2600 SWALL:TYRA_ECOLI (SWALL:P07023) (373 aa) fasta scores: E(): 1.6e-123, 87.13% id in 373 aa.
  
  
 0.677
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
     
 0.672
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
  
  
 0.647
radC
DNA repair protein; Similar to Escherichia coli DNA repair protein RadC or b3638 SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 1.1e-50, 58.14% id in 215 aa; Belongs to the UPF0758 family. YicR subfamily.
 
    0.641
ECA0593
Similar to Vibrio cholerae DNA repair protein RadC homolog SWALL:RADC_VIBCH (SWALL:Q9KVC9) (224 aa) fasta scores: E(): 2.2e-28, 55.47% id in 137 aa, and to Escherichia coli DNA repair protein RadC SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 2.4e-26, 50.38% id in 129 aa; Belongs to the UPF0758 family.
 
    0.633
ECA2855
Conserved hypothetical protein; Similar to Shigella flexneri intergenic-region protein yees or sf2996 SWALL:AAN44477 (EMBL:AE015313) (163 aa) fasta scores: E(): 4.9e-27, 50.65% id in 152 aa, and to Escherichia coli intergenic-region protein SWALL:Q8VRA3 (EMBL:AF447814) (163 aa) fasta scores: E(): 5.7e-27, 50.65% id in 152 aa, and to Escherichia coli DNA repair protein RadC or b3638 SWALL:RADC_ECOLI (SWALL:P25531) (222 aa) fasta scores: E(): 5.6e-23, 47.51% id in 141 aa; Belongs to the UPF0758 family.
 
    0.632
bioH
Putative biotin biosynthesis protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
     
 0.616
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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