| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA0462 | glpG | ECA0462 | ECA4138 | Similar to Oryctolagus cuniculus 5-formyltetrahydrofolate cyclo-ligase MthfS SWALL:FTHC_RABIT (SWALL:P80405) (201 aa) fasta scores: E(): 2.9e-11, 28.35% id in 201 aa, and to Yersinia pestis putative 5-formyltetrahydrofolate cyclo-ligase-family protein ypo0913 or y3300 SWALL:Q8ZHI0 (EMBL:AJ414145) (198 aa) fasta scores: E(): 1.2e-51, 67.87% id in 193 aa. | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.643 |
| amiB | amiC | ECA3937 | ECA1000 | Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiB precursor AmiB or b4169 SWALL:AMIB_ECOLI (SWALL:P26365) (445 aa) fasta scores: E(): 5.9e-74, 65.34% id in 430 aa. | Similar to Escherichia coli O6 N-acetylmuramoyl-L-alanine amidase amic precursor AmiC or b2817 or c3411 SWALL:AMIC_ECOLI (SWALL:Q46929) (417 aa) fasta scores: E(): 2.2e-113, 72.46% id in 414 aa, and to Yersinia pestis N-acetylmuramoyl-L-alanine amidase amic ypo1023 SWALL:Q8ZH85 (EMBL:AJ414146) (416 aa) fasta scores: E(): 1.3e-120, 77.31% id in 410 aa. | 0.960 |
| amiB | glpG | ECA3937 | ECA4138 | Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiB precursor AmiB or b4169 SWALL:AMIB_ECOLI (SWALL:P26365) (445 aa) fasta scores: E(): 5.9e-74, 65.34% id in 430 aa. | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.603 |
| amiC | amiB | ECA1000 | ECA3937 | Similar to Escherichia coli O6 N-acetylmuramoyl-L-alanine amidase amic precursor AmiC or b2817 or c3411 SWALL:AMIC_ECOLI (SWALL:Q46929) (417 aa) fasta scores: E(): 2.2e-113, 72.46% id in 414 aa, and to Yersinia pestis N-acetylmuramoyl-L-alanine amidase amic ypo1023 SWALL:Q8ZH85 (EMBL:AJ414146) (416 aa) fasta scores: E(): 1.3e-120, 77.31% id in 410 aa. | Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiB precursor AmiB or b4169 SWALL:AMIB_ECOLI (SWALL:P26365) (445 aa) fasta scores: E(): 5.9e-74, 65.34% id in 430 aa. | 0.960 |
| amiC | glpG | ECA1000 | ECA4138 | Similar to Escherichia coli O6 N-acetylmuramoyl-L-alanine amidase amic precursor AmiC or b2817 or c3411 SWALL:AMIC_ECOLI (SWALL:Q46929) (417 aa) fasta scores: E(): 2.2e-113, 72.46% id in 414 aa, and to Yersinia pestis N-acetylmuramoyl-L-alanine amidase amic ypo1023 SWALL:Q8ZH85 (EMBL:AJ414146) (416 aa) fasta scores: E(): 1.3e-120, 77.31% id in 410 aa. | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.564 |
| clpP | clpS | ECA1148 | ECA2657 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.918 |
| clpP | glpG | ECA1148 | ECA4138 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.766 |
| clpP | lon | ECA1148 | ECA1150 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent protease la; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.923 |
| clpS | clpP | ECA2657 | ECA1148 | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.918 |
| clpS | glpG | ECA2657 | ECA4138 | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.790 |
| clpS | lon | ECA2657 | ECA1150 | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | ATP-dependent protease la; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.561 |
| glpE | glpG | ECA4139 | ECA4138 | Thiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.840 |
| glpE | glpR | ECA4139 | ECA4137 | Thiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. | Similar to Escherichia coli glycerol-3-phosphate regulon repressor GlpR or b3423 SWALL:GLPR_ECOLI (SWALL:P09392) (252 aa) fasta scores: E(): 4.8e-76, 76.58% id in 252 aa. | 0.518 |
| glpE | malP | ECA4139 | ECA4136 | Thiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. | Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | 0.968 |
| glpG | ECA0462 | ECA4138 | ECA0462 | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Similar to Oryctolagus cuniculus 5-formyltetrahydrofolate cyclo-ligase MthfS SWALL:FTHC_RABIT (SWALL:P80405) (201 aa) fasta scores: E(): 2.9e-11, 28.35% id in 201 aa, and to Yersinia pestis putative 5-formyltetrahydrofolate cyclo-ligase-family protein ypo0913 or y3300 SWALL:Q8ZHI0 (EMBL:AJ414145) (198 aa) fasta scores: E(): 1.2e-51, 67.87% id in 193 aa. | 0.643 |
| glpG | amiB | ECA4138 | ECA3937 | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiB precursor AmiB or b4169 SWALL:AMIB_ECOLI (SWALL:P26365) (445 aa) fasta scores: E(): 5.9e-74, 65.34% id in 430 aa. | 0.603 |
| glpG | amiC | ECA4138 | ECA1000 | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Similar to Escherichia coli O6 N-acetylmuramoyl-L-alanine amidase amic precursor AmiC or b2817 or c3411 SWALL:AMIC_ECOLI (SWALL:Q46929) (417 aa) fasta scores: E(): 2.2e-113, 72.46% id in 414 aa, and to Yersinia pestis N-acetylmuramoyl-L-alanine amidase amic ypo1023 SWALL:Q8ZH85 (EMBL:AJ414146) (416 aa) fasta scores: E(): 1.3e-120, 77.31% id in 410 aa. | 0.564 |
| glpG | clpP | ECA4138 | ECA1148 | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.766 |
| glpG | clpS | ECA4138 | ECA2657 | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.790 |
| glpG | glpE | ECA4138 | ECA4139 | Putative membrane protein; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | Thiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. | 0.840 |