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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECA4140Putative glyoxalase; Similar to Xenorhabdus nematophilus glyoxalase GloA SWALL:Q8RLU7 (EMBL:AY077466) (132 aa) fasta scores: E(): 3.7e-36, 74.26% id in 136 aa, and to Clostridium acetobutylicum predicted aldoketomutase of glyoxalase i family cac2466 SWALL:Q97GA3 (EMBL:AE007746) (132 aa) fasta scores: E(): 5.2e-18, 46.66% id in 135 aa. (137 aa)    
Predicted Functional Partners:
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.967
glpE
Thiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
 
 
  0.617
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.597
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
    0.536
birA
Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.497
glpD
Similar to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD or GlyD or b3426 SWALL:GLPD_ECOLI (SWALL:P13035) (501 aa) fasta scores: E(): 9e-157, 76.59% id in 500 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
    0.457
sdhC
Similar to Escherichia coli, and Escherichia coli O157:H7 succinate dehydrogenase cytochrome b-556 subunit SdhC or CybA or b0721 or z0875 or ecs0746 SWALL:DHSC_ECOLI (SWALL:P10446) (129 aa) fasta scores: E(): 1.1e-38, 79.06% id in 129 aa.
   
    0.448
tadA
Putative cytidine and deoxycytidylate deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
  
 0.436
cutD
Putative pyruvate formate-lyase activating enzyme; Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).
  
 
  0.420
hyfH
Similar to Escherichia coli hydrogenase-4 component H HyfH or b2488 SWALL:HYFH_ECOLI (SWALL:P77423) (181 aa) fasta scores: E(): 3.7e-39, 61.44% id in 166 aa.
  
 
  0.418
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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