STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (367 aa)    
Predicted Functional Partners:
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I [includes: aspartokinase I; homoserine dehydrogenase I] thra or thra1 or thra2 or b0002 SWALL:AK1H_ECOLI (SWALL:P00561) (820 aa) fasta scores: E(): 0, 82.41% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 0.995
metL
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase II MetL or MetM or b3940 SWALL:AK2H_ECOLI (SWALL:P00562) (809 aa) fasta scores: E(): 0, 83.12% id in 800 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 0.995
lysC
Similar to Escherichia coli lysine-sensitive aspartokinase III LysC or Apk or b4024 SWALL:AK3_ECOLI (SWALL:P08660) (449 aa) fasta scores: E(): 9.4e-136, 80.89% id in 445 aa; Belongs to the aspartokinase family.
  
 
 0.979
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 
 0.936
ECA3763
Similar to Bacillus subtilis dihydrodipicolinate synthase DapA SWALL:DAPA_BACSU (SWALL:Q04796) (290 aa) fasta scores: E(): 2.9e-26, 34.16% id in 281 aa, and to Escherichia coli O6 putative dihydrodipicolinate synthase c0761 SWALL:AAN79234 (EMBL:AE016757) (295 aa) fasta scores: E(): 1.9e-75, 67.91% id in 293 aa; Belongs to the DapA family.
  
 
 0.936
ECA1002
Putative dihydrodipicolinate synthase; Similar to Escherichia coli, and Shigella flexneri dihydrodipicolinate synthase DapA or b2478 or sf2521 SWALL:DAPA_ECOLI (SWALL:P05640) (292 aa) fasta scores: E(): 2.8e-20, 30.45% id in 289 aa, and to Ralstonia solanacearum dihydrodipicolinate synthase dapa or rsc1145 or rs04756 SWALL:DAPA_RALSO (SWALL:Q8Y099) (294 aa) fasta scores: E(): 2.5e-26, 30.71% id in 280 aa; Belongs to the DapA family.
  
 
 0.934
ECA4425
Putative dihydrodipicolinate synthetase; Similar to Bradyrhizobium japonicum Bll7272 protein bll7272 SWALL:BAC52537 (EMBL:AP005961) (291 aa) fasta scores: E(): 3.2e-70, 65.97% id in 288 aa, and to Pseudomonas aeruginosa probable dihydrodipicolinate synthetase pa0223 SWALL:Q9I6R5 (EMBL:AE004460) (293 aa) fasta scores: E(): 8.8e-24, 32.29% id in 288 aa.
  
 
 0.932
dat
Similar to Acinetobacter baumannii diaminobutyrate--2-oxoglutarate aminotransferase Dat SWALL:DAT_ACIBA (SWALL:P56744) (445 aa) fasta scores: E(): 3.4e-101, 67.19% id in 442 aa, and to Haemophilus influenzae diaminobutyrate--2-oxoglutarate aminotransferase Dat or hi0949 SWALL:DAT_HAEIN (SWALL:P44951) (454 aa) fasta scores: E(): 9.9e-110, 64.15% id in 438 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.907
thrC
Threonine synthase; Similar to Escherichia coli threonine synthase ThrC or b0004 SWALL:THRC_ECOLI (SWALL:P00934) (428 aa) fasta scores: E(): 4.2e-135, 80.51% id in 426 aa.
  
 
 0.782
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
  
 0.771
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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