Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECA4161Similar to Alteromonas sp. beta-hexosaminidase A precursor Cht60 SWALL:HEXA_ALTSO (SWALL:P48823) (598 aa) fasta scores: E(): 1.2e-60, 37.11% id in 590 aa, and to Ralstonia solanacearum putative hydrolase glycosidase protein rsc0769 or rs05085 SWALL:Q8Y1C1 (EMBL:AL646060) (734 aa) fasta scores: E(): 3.2e-82, 45.02% id in 653 aa. (598 aa)    
Predicted Functional Partners:
anmK
Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
  
 0.774
nagZ
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
  
  
 
0.756
murQ
Putative phophosugar-binding protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
 
  
 0.660
amiB
Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiB precursor AmiB or b4169 SWALL:AMIB_ECOLI (SWALL:P26365) (445 aa) fasta scores: E(): 5.9e-74, 65.34% id in 430 aa.
    
 0.601
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
  
 0.532
ECA0077
Putative exported protein; Similar to Pyrococcus abyssi related beta-lactamase precursor Pbp SWALL:Q9V2D6 (EMBL:AJ248283) (447 aa) fasta scores: E(): 2.5e-14, 22.94% id in 340 aa, and to Bacillus cereus alkaline D-peptidase adP SWALL:P94288 (EMBL:D86380) (388 aa) fasta scores: E(): 1.7e-10, 29.52% id in 254 aa.
 
 
 0.524
amiC
Similar to Escherichia coli O6 N-acetylmuramoyl-L-alanine amidase amic precursor AmiC or b2817 or c3411 SWALL:AMIC_ECOLI (SWALL:Q46929) (417 aa) fasta scores: E(): 2.2e-113, 72.46% id in 414 aa, and to Yersinia pestis N-acetylmuramoyl-L-alanine amidase amic ypo1023 SWALL:Q8ZH85 (EMBL:AJ414146) (416 aa) fasta scores: E(): 1.3e-120, 77.31% id in 410 aa.
    
 0.516
tolA
TolA protein; Similar to Erwinia chrysanthemi TolA protein TolA SWALL:Q937K4 (EMBL:AJ297885) (395 aa) fasta scores: E(): 7.1e-61, 79.44% id in 394 aa, and to Escherichia coli tola protein TolA or Cim or ExcC or Lky or b0739 SWALL:TOLA_ECOLI (SWALL:P19934) (421 aa) fasta scores: E(): 6.5e-29, 58.72% id in 424 aa.
  
  
 0.480
mpl
udp-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
  
   
 0.411
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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