STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4182Similar to Yersinia pestis hypothetical protein ypo3844 or y0386 SWALL:Q8ZAF8 (EMBL:AJ414159) (234 aa) fasta scores: E(): 1.8e-68, 73.93% id in 234 aa, and to Salmonella typhi hypothetical protein Sty3611 SWALL:Q8Z3A7 (EMBL:AL627279) (235 aa) fasta scores: E(): 4.6e-60, 64.68% id in 235 aa. (234 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
    0.921
xerC
Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the t [...]
  
    0.882
ECA4180
Putative hydrolase; Similar to Escherichia coli, and Shigella flexneri hypothetical protein yigb or b3812 or sf3890 SWALL:YIGB_ECOLI (SWALL:P23306) (238 aa) fasta scores: E(): 1.4e-60, 66.8% id in 238 aa, and to Yersinia pestis putative haloacid dehalogenase-like hydrolase ypo3842 or y0388 SWALL:Q8ZAG0 (EMBL:AJ414159) (238 aa) fasta scores: E(): 3.4e-60, 66.38% id in 238 aa.
  
    0.825
ECA2203
Similar to Yersinia pestis putative exported protein ypo2305 or y2136 SWALL:Q8ZE77 (EMBL:AJ414151) (317 aa) fasta scores: E(): 2.4e-78, 69.9% id in 319 aa, and to Shigella flexneri orf, conserved hypothetical protein sf1625 SWALL:AAN43208 (EMBL:AE015183) (314 aa) fasta scores: E(): 8.2e-74, 67.82% id in 317 aa.
  
     0.751
hemX
Similar to Escherichia coli putative uroporphyrin-III C-methyltransferase HemX or b3803 SWALL:HEMX_ECOLI (SWALL:P09127) (393 aa) fasta scores: E(): 5.1e-71, 60.54% id in 370 aa.
 
    0.682
damX
DamX protein; Non-essential cell division protein.
  
    0.676
ECA4231
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri protein yife or b3764 or c4686 or z5276 or ecs4699 or sf3840 SWALL:AAN45278 (EMBL:M87049) (112 aa) fasta scores: E(): 2.1e-36, 79.46% id in 112 aa, and to Yersinia pestis hypothetical protein Ypo3903 SWALL:Q8ZAA8 (EMBL:AJ414159) (112 aa) fasta scores: E(): 7.3e-36, 81.25% id in 112 aa.
  
     0.668
lptC
Putative exported protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
     0.666
hemY
Porphyrin biosynthetic protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri HemY protein HemY or b3802 or c4721 or z5316 or ecs4732 or sf3874 SWALL:HEMY_ECOLI (SWALL:P09128) (398 aa) fasta scores: E(): 1.3e-109, 73.02% id in 393 aa, and to Salmonella typhi porphyrin biosynthetic protein sty3624 SWALL:Q8Z398 (EMBL:AL627279) (399 aa) fasta scores: E(): 7e-108, 71.24% id in 393 aa.
 
     0.653
wzyE
Putative ECA polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.
  
     0.648
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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