node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cpdA | cyaA | ECA0750 | ECA4187 | Putative calcineurin-like phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | 0.909 |
cpdA | cyaB | ECA0750 | ECA2795 | Putative calcineurin-like phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Adenylate cyclase; Similar to Aeromonas hydrophila adenylate cyclase CyaB SWALL:O69199 (EMBL:AJ223730) (191 aa) fasta scores: E(): 1.8e-29, 46.55% id in 174 aa, and to Yersinia pestis adenylate cyclase 2 CyaB or ypo1178 or y3011 SWALL:Q8ZGU9 (EMBL:AJ414146) (179 aa) fasta scores: E(): 5.7e-34, 52.51% id in 179 aa. | 0.906 |
cpdA | icc | ECA0750 | ECA0333 | Putative calcineurin-like phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | cAMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.927 |
cpdA | mazG | ECA0750 | ECA3568 | Putative calcineurin-like phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | 0.900 |
cpdA | pdeA | ECA0750 | ECA4245 | Putative calcineurin-like phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.924 |
cyaA | cpdA | ECA4187 | ECA0750 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Putative calcineurin-like phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.909 |
cyaA | cyaB | ECA4187 | ECA2795 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Adenylate cyclase; Similar to Aeromonas hydrophila adenylate cyclase CyaB SWALL:O69199 (EMBL:AJ223730) (191 aa) fasta scores: E(): 1.8e-29, 46.55% id in 174 aa, and to Yersinia pestis adenylate cyclase 2 CyaB or ypo1178 or y3011 SWALL:Q8ZGU9 (EMBL:AJ414146) (179 aa) fasta scores: E(): 5.7e-34, 52.51% id in 179 aa. | 0.919 |
cyaA | icc | ECA4187 | ECA0333 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | cAMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.950 |
cyaA | mazG | ECA4187 | ECA3568 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | 0.900 |
cyaA | ndk | ECA4187 | ECA3224 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
cyaA | nrdD | ECA4187 | ECA0375 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Similar to Escherichia coli anaerobic ribonucleoside-triphosphate reductase NrdD or b4238 SWALL:NRDD_ECOLI (SWALL:P28903) (712 aa) fasta scores: E(): 0, 85.97% id in 713 aa. | 0.918 |
cyaA | pdeA | ECA4187 | ECA4245 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.920 |
cyaA | pykA | ECA4187 | ECA2481 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Pyruvate kinase II; Similar to Escherichia coli pyruvate kinase ii PykA or b1854 SWALL:KPY2_ECOLI (SWALL:P21599) (479 aa) fasta scores: E(): 2.7e-156, 91.23% id in 479 aa. | 0.901 |
cyaA | pykF | ECA4187 | ECA1867 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Pyruvate kinase; Similar to Escherichia coli, and Escherichia coli O157:H7 pyruvate kinase I PykF or b1676 or z2704 or ecs2383 SWALL:KPY1_ECOLI (SWALL:P14178) (470 aa) fasta scores: E(): 4.4e-139, 84.68% id in 470 aa. | 0.901 |
cyaA | spoT | ECA4187 | ECA0038 | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
cyaB | cpdA | ECA2795 | ECA0750 | Adenylate cyclase; Similar to Aeromonas hydrophila adenylate cyclase CyaB SWALL:O69199 (EMBL:AJ223730) (191 aa) fasta scores: E(): 1.8e-29, 46.55% id in 174 aa, and to Yersinia pestis adenylate cyclase 2 CyaB or ypo1178 or y3011 SWALL:Q8ZGU9 (EMBL:AJ414146) (179 aa) fasta scores: E(): 5.7e-34, 52.51% id in 179 aa. | Putative calcineurin-like phosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.906 |
cyaB | cyaA | ECA2795 | ECA4187 | Adenylate cyclase; Similar to Aeromonas hydrophila adenylate cyclase CyaB SWALL:O69199 (EMBL:AJ223730) (191 aa) fasta scores: E(): 1.8e-29, 46.55% id in 174 aa, and to Yersinia pestis adenylate cyclase 2 CyaB or ypo1178 or y3011 SWALL:Q8ZGU9 (EMBL:AJ414146) (179 aa) fasta scores: E(): 5.7e-34, 52.51% id in 179 aa. | Adenylate cyclase; Similar to Erwinia chrysanthemi adenylate cyclase Cya SWALL:CYAA_ERWCH (SWALL:P40130) (851 aa) fasta scores: E(): 0, 89.33% id in 853 aa, and to Escherichia coli adenylate cyclase CyaA or Cya or b3806 SWALL:CYAA_ECOLI (SWALL:P00936) (848 aa) fasta scores: E(): 0, 82.19% id in 848 aa; Belongs to the adenylyl cyclase class-1 family. | 0.919 |
cyaB | icc | ECA2795 | ECA0333 | Adenylate cyclase; Similar to Aeromonas hydrophila adenylate cyclase CyaB SWALL:O69199 (EMBL:AJ223730) (191 aa) fasta scores: E(): 1.8e-29, 46.55% id in 174 aa, and to Yersinia pestis adenylate cyclase 2 CyaB or ypo1178 or y3011 SWALL:Q8ZGU9 (EMBL:AJ414146) (179 aa) fasta scores: E(): 5.7e-34, 52.51% id in 179 aa. | cAMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.906 |
cyaB | mazG | ECA2795 | ECA3568 | Adenylate cyclase; Similar to Aeromonas hydrophila adenylate cyclase CyaB SWALL:O69199 (EMBL:AJ223730) (191 aa) fasta scores: E(): 1.8e-29, 46.55% id in 174 aa, and to Yersinia pestis adenylate cyclase 2 CyaB or ypo1178 or y3011 SWALL:Q8ZGU9 (EMBL:AJ414146) (179 aa) fasta scores: E(): 5.7e-34, 52.51% id in 179 aa. | Conserved hypothetical protein; Similar to Escherichia coli, and Escherichia coli O157:H7 MazG protein MazG or b2781 or z4096 or ecs3641 SWALL:MAZG_ECOLI (SWALL:P33646) (263 aa) fasta scores: E(): 2.2e-72, 73.18% id in 261 aa, and to Yersinia pestis hypothetical protein ypo3378 or MazG or y0812 SWALL:Q8ZBN0 (EMBL:AJ414156) (280 aa) fasta scores: E(): 3.6e-78, 79.54% id in 264 aa. | 0.900 |
cyaB | ndk | ECA2795 | ECA3224 | Adenylate cyclase; Similar to Aeromonas hydrophila adenylate cyclase CyaB SWALL:O69199 (EMBL:AJ223730) (191 aa) fasta scores: E(): 1.8e-29, 46.55% id in 174 aa, and to Yersinia pestis adenylate cyclase 2 CyaB or ypo1178 or y3011 SWALL:Q8ZGU9 (EMBL:AJ414146) (179 aa) fasta scores: E(): 5.7e-34, 52.51% id in 179 aa. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |