STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
putABifunctional PutA protein [includes: proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1322 aa)    
Predicted Functional Partners:
putP
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.990
ECA3764
Similar to Pseudomonas aeruginosa probable sodium:solute symporter pa0287 SWALL:Q9I6K3 (EMBL:AE004466) (461 aa) fasta scores: E(): 4.1e-21, 23.02% id in 456 aa, and to Vibrio vulnificus na+/proline symporter vv20592 SWALL:AAO07538 (EMBL:AE016810) (492 aa) fasta scores: E(): 8.5e-19, 25.05% id in 455 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.961
gdhA
Similar to Escherichia coli NADP-specific glutamate dehydrogenase GdhA or b1761 SWALL:DHE4_ECOLI (SWALL:P00370) (447 aa) fasta scores: E(): 7.7e-145, 85.01% id in 447 aa; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.955
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.955
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.951
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
  
 
 0.947
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
    
 0.944
glnA
Glutamine synthetase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri glutamine synthetase GlnA or b3870 or c4819 or z5406 or ecs4792 or sf3940 SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 3e-170, 90.17% id in 468 aa.
   
 
 0.939
dat-2
Similar to Staphylococcus haemolyticus D-alanine aminotransferase Dat SWALL:DAAA_STAHA (SWALL:P54694) (282 aa) fasta scores: E(): 4.8e-36, 38.57% id in 280 aa, and to Agrobacterium tumefaciens D-alanine aminotransferase Dat or atu5473 or agr_pat_698 SWALL:Q8UJK4 (EMBL:AE008968) (290 aa) fasta scores: E(): 6.7e-61, 55.39% id in 278 aa.
   
 0.936
aatA
Similar to Rhizobium meliloti aspartate aminotransferase A AatA or r02325 or smc01578 SWALL:AATA_RHIME (SWALL:Q02635) (400 aa) fasta scores: E(): 5.9e-80, 50.62% id in 399 aa, and to Agrobacterium tumefaciens aspartate aminotransferase A AatA or atu4278 or agr_l_1171 SWALL:Q8U821 (EMBL:AE009356) (412 aa) fasta scores: E(): 7.9e-115, 72.04% id in 397 aa.
   
 
 0.922
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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