STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvYLysR-family transcriptional activator of ilvC; Similar to Escherichia coli transcriptional activator protein IlvY or b3773 SWALL:ILVY_ECOLI (SWALL:P05827) (297 aa) fasta scores: E(): 8e-86, 73.98% id in 296 aa; Belongs to the LysR transcriptional regulatory family. (296 aa)    
Predicted Functional Partners:
ECA4223
Putative exported protein; Similar to Shewanella oneidensis conserved hypothetical protein so0112 SWALL:AAN53199 (EMBL:AE015462) (207 aa) fasta scores: E(): 2.1e-05, 28.85% id in 201 aa, and to Xanthomonas axonopodis hypothetical protein Xac3205 SWALL:Q8PHP4 (EMBL:AE011966) (389 aa) fasta scores: E(): 6.4e-05, 26.4% id in 231 aa.
       0.779
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
    0.749
ECA4427
LysR-family transcriptional regulator; Similar to Agrobacterium tumefaciens regulatory protein NocR or atu6029 or agr_pti_70 SWALL:NOCR_AGRT5 (SWALL:Q00678) (300 aa) fasta scores: E(): 1.4e-28, 35.29% id in 289 aa, and to Rhizobium meliloti octopine catabolism/uptake operon regulatory protein OccR SWALL:OCCR_RHIME (SWALL:P72294) (297 aa) fasta scores: E(): 5.8e-23, 36.58% id in 287 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.681
nac
Partial CDS. Similar to the N-terminal region of Escherichia coli nitrogen assimilation regulatory protein Nac or b1988 SWALL:NAC_ECOLI (SWALL:Q47005) (305 aa) fasta scores: E(): 1.4e-23, 77.77% id in 90 aa.
  
     0.642
ECA0131
Similar to Pseudomonas aeruginosa probable transcriptional regulator pa5085 SWALL:Q9HU98 (EMBL:AE004921) (318 aa) fasta scores: E(): 9.5e-27, 36.15% id in 307 aa, and to Salmonella typhimurium, and Salmonella typhi positive transcriptional regulator LysR SWALL:Q8XGD5 (EMBL:AE008838) (311 aa) fasta scores: E(): 1.8e-15, 26.66% id in 300 aa, and to Escherichia coli transcriptional activator protein LysR SWALL:LYSR_ECOLI (SWALL:P03030) (311 aa) fasta scores: E(): 3.2e-13, 27.79% id in 277 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.539
ECA2642
Similar to Pseudomonas putida transcriptional regulator, LysR family pp4522 SWALL:AAN70096 (EMBL:AE016791) (297 aa) fasta scores: E(): 5.6e-24, 29.64% id in 280 aa, and to Rhizobium loti transcriptional regulator mlr6990 SWALL:Q987M7 (EMBL:AP003010) (299 aa) fasta scores: E(): 4.7e-18, 30.45% id in 266 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.538
ECA0068
Similar to Pseudomonas aeruginosa probable transcriptional regulator pa3225 SWALL:Q9HZ15 (EMBL:AE004745) (309 aa) fasta scores: E(): 1.4e-30, 38.11% id in 286 aa, and to Escherichia coli hypothetical transcriptional regulator YeeY SWALL:YEEY_ECOLI (SWALL:P76369) (309 aa) fasta scores: E(): 7.8e-10, 28.34% id in 247 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.490
ECA3634
Similar to Brucella melitensis transcriptional regulatory protein, LysR family bmeii1135 SWALL:Q8YAW6 (EMBL:AE009745) (297 aa) fasta scores: E(): 5.1e-26, 30.66% id in 287 aa, and to Rhizobium meliloti putative transcription regulator protein r02876 or smc02984 SWALL:Q92LY6 (EMBL:AL591792) (297 aa) fasta scores: E(): 2.4e-28, 33.33% id in 288 aa.
  
     0.474
lysR
Similar to Escherichia coli transcriptional activator protein LysR or b2839 SWALL:LYSR_ECOLI (SWALL:P03030) (311 aa) fasta scores: E(): 1e-81, 72.48% id in 298 aa; Belongs to the LysR transcriptional regulatory family.
  
     0.471
ECA3561
Similar to Streptomyces antibioticus transcriptional regulatory protein AraB AbaB SWALL:ARAB_STRAT (SWALL:P52659) (301 aa) fasta scores: E(): 4e-16, 32.78% id in 302 aa, and to Streptomyces coelicolor putative LysR-family transcriptional regulator sco6801 or sc1a2.10 SWALL:Q9L231 (EMBL:AL939129) (300 aa) fasta scores: E(): 1.2e-09, 30.9% id in 288 aa.
  
     0.457
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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