Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA4223Putative exported protein; Similar to Shewanella oneidensis conserved hypothetical protein so0112 SWALL:AAN53199 (EMBL:AE015462) (207 aa) fasta scores: E(): 2.1e-05, 28.85% id in 201 aa, and to Xanthomonas axonopodis hypothetical protein Xac3205 SWALL:Q8PHP4 (EMBL:AE011966) (389 aa) fasta scores: E(): 6.4e-05, 26.4% id in 231 aa. (266 aa)    
Predicted Functional Partners:
ilvY
LysR-family transcriptional activator of ilvC; Similar to Escherichia coli transcriptional activator protein IlvY or b3773 SWALL:ILVY_ECOLI (SWALL:P05827) (297 aa) fasta scores: E(): 8e-86, 73.98% id in 296 aa; Belongs to the LysR transcriptional regulatory family.
       0.782
ECA0117
Putative exported protein; Similar to Xanthomonas axonopodis hypothetical protein Xac2610 SWALL:Q8PJC5 (EMBL:AE011901) (267 aa) fasta scores: E(): 6.7e-11, 30.18% id in 159 aa, and to Yersinia pestis putative exported protein ypo0702 or y3476 SWALL:AAM87024 (EMBL:AJ414144) (331 aa) fasta scores: E(): 0.00098, 27.43% id in 113 aa.
  
     0.718
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.514
ECA4146
Similar to Ralstonia solanacearum hypothetical protein rsp0177 or rs04689 SWALL:Q8XTD6 (EMBL:AL646077) (740 aa) fasta scores: E(): 0.0057, 25.85% id in 410 aa.
  
     0.470
ECA3479
Hypothetical protein; Weakly similar to Ralstonia solanacearum hypothetical protein rsp0177 or rs04689 SWALL:Q8XTD6 (EMBL:AL646077) (740 aa) fasta scores: E(): 0.00056, 26.34% id in 410 aa.
  
     0.467
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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