STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4230Probable magnesium-chelatase; Similar to Haemophilus influenzae competence protein ComM or hi1117 SWALL:COMM_HAEIN (SWALL:P45049) (509 aa) fasta scores: E(): 2.2e-110, 64.22% id in 506 aa, and to Yersinia pestis putative magnesium chelatase family protein ypo3902 SWALL:Q8ZAA9 (EMBL:AJ414159) (507 aa) fasta scores: E(): 5e-130, 73.96% id in 507 aa. (508 aa)    
Predicted Functional Partners:
ECA4133
Similar to Yersinia pestis hypothetical protein ypo0128 ypo0128 or y3906 SWALL:AAM87448 (EMBL:AJ414141) (233 aa) fasta scores: E(): 7.3e-52, 56.22% id in 233 aa, and to Salmonella typhi putative competence protein sty4286 SWALL:Q8Z222 (EMBL:AL627281) (227 aa) fasta scores: E(): 7.7e-46, 53.21% id in 233 aa.
 
  
 0.890
smf
Conserved hypothetical protein; Similar to Escherichia coli Smf protein Smf or b3285/b3286 SWALL:SMF_ECOLI (SWALL:P30852) (374 aa) fasta scores: E(): 1.5e-79, 57.75% id in 374 aa, and to Yersinia pestis hypothetical protein ypo0243 ypo0243 or Smf1 or y4024 SWALL:Q8ZJ78 (EMBL:AJ414141) (373 aa) fasta scores: E(): 1.6e-82, 60.32% id in 373 aa.
 
 
 0.877
ECA1153
Putative exported protein; Similar to Salmonella typhimurium, and Salmonella typhi putative DNA uptake protein and related dna-binding proteins ybav or stm0453 or sty0495 SWALL:Q8XGV0 (EMBL:AE008716) (124 aa) fasta scores: E(): 5.3e-15, 48.78% id in 123 aa, and to Escherichia coli, and Shigella flexneri hypothetical protein ybav precursor ybav or b0442 or sf0387 SWALL:AAN42043 (EMBL:AE000150) (123 aa) fasta scores: E(): 2.8e-13, 49.19% id in 124 aa.
  
  
 0.608
ECA2558
Similar to Yersinia pestis putative membrane protein ypo1394 or y2778 SWALL:Q8ZGB0 (EMBL:AJ414148) (763 aa) fasta scores: E(): 7.2e-161, 50.19% id in 763 aa, and to Salmonella typhi putative competence-related protein sty0984 SWALL:Q8Z802 (EMBL:AL627268) (754 aa) fasta scores: E(): 7.2e-126, 42.52% id in 762 aa.
 
  
 0.592
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
 
     0.567
ruvC
Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.526
recG
Putative ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
   
 0.522
hofQ
Putative type II secretion system protein; Similar to Escherichia coli protein transport protein HofQ precursor HofQ or HopQ or b3391 SWALL:HOFQ_ECOLI (SWALL:P34749) (412 aa) fasta scores: E(): 3.1e-71, 52.3% id in 390 aa, and to Yersinia pestis putative membrane transport protein ypo0150 or hofq or y3932 SWALL:Q8ZJF8 (EMBL:AJ414141) (374 aa) fasta scores: E(): 3.9e-84, 62.89% id in 380 aa.
  
   
 0.516
recA
RecA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
  
 0.492
nnrE
Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
 
     0.454
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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