STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
btuBVitamin B12 receptor precursor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (615 aa)    
Predicted Functional Partners:
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
  
 0.824
ompA
Outer-membrane protein A; Similar to Erwinia carotovora putative outer-membrane protein a precursor OmpA SWALL:Q9RM69 (EMBL:AJ249340) (367 aa) fasta scores: E(): 2.6e-120, 90.32% id in 372 aa, and to Serratia marcescens outer membrane protein a precursor OmpA SWALL:OMPA_SERMA (SWALL:P04845) (359 aa) fasta scores: E(): 4.8e-71, 75.61% id in 369 aa; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
 0.773
tolB
TolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
    
 
 0.754
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.733
ECA0928
TonB-like protein; Similar to Salmonella typhimurium TonB protein SWALL:TONB_SALTY (SWALL:P25945) (242 aa) fasta scores: E(): 6.8e-09, 35.93% id in 192 aa, and to Escherichia coli TonB protein SWALL:TONB_ECOLI (SWALL:P02929) (239 aa) fasta scores: E(): 6.5e-07, 37.91% id in 182 aa.
 
 
 
 0.699
ECA1272
TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.672
tonB-2
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.656
ECA0877
TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
   
 
 0.632
ECA4369
Similar to Salmonella typhi hypothetical protein yhjq or sty4180 SWALL:Q8Z292 (EMBL:AL627281) (250 aa) fasta scores: E(): 7.1e-50, 51.22% id in 246 aa, and to Escherichia coli O6 hypothetical protein yhjq or c4346 SWALL:AAN82782 (EMBL:AE016768) (250 aa) fasta scores: E(): 4.3e-49, 51.04% id in 239 aa.
  
 
 
 0.622
tsx
Nucleoside-specific channel-forming protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri nucleoside-specific channel-forming protein Tsx precursor Tsx or NupA or b0411 or z0512 or ecs0464 or sf0348 SWALL:TSX_ECOLI (SWALL:P22786) (294 aa) fasta scores: E(): 3.1e-92, 73.46% id in 294 aa.
     
 0.613
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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