STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
btuBVitamin B12 receptor precursor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (615 aa)    
Predicted Functional Partners:
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
 0.837
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.793
ECA0928
TonB-like protein; Similar to Salmonella typhimurium TonB protein SWALL:TONB_SALTY (SWALL:P25945) (242 aa) fasta scores: E(): 6.8e-09, 35.93% id in 192 aa, and to Escherichia coli TonB protein SWALL:TONB_ECOLI (SWALL:P02929) (239 aa) fasta scores: E(): 6.5e-07, 37.91% id in 182 aa.
 
 
 
 0.767
ECA0877
TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
   
 
 0.715
ECA1272
TonB-like protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.698
tonB-2
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.682
tolB
TolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
      
 0.655
ompN
Similar to Escherichia coli outer membrane protein N precursor OmpN or b1377 SWALL:OMPN_ECOLI (SWALL:P77747) (377 aa) fasta scores: E(): 1.1e-76, 53.86% id in 388 aa.
    
 
 0.648
ECA1099
Large repetitive protein; Similar to Salmonella typhi protein sty2875 SWALL:Q8Z4I1 (EMBL:AL627276) (3624 aa) fasta scores: E(): 1.9e-41, 26.46% id in 3438 aa, and to Yersinia pestis putative autotransporter protein yaph or ypo1004 SWALL:Q8ZHA1 (EMBL:AJ414146) (3705 aa) fasta scores: E(): 8e-31, 23.21% id in 3584 aa.
    
   0.640
ECA1100
Similar to Escherichia coli O157:H7 hypothetical protein z0609 or ecs0541 SWALL:Q8XD19 (EMBL:AE005228) (1461 aa) fasta scores: E(): 1.7e-61, 34.15% id in 1253 aa, and to Salmonella typhi proline/threonine-rich protein SWALL:Q9X6M3 (EMBL:AF139831) (1605 aa) fasta scores: E(): 1e-14, 27.68% id in 1239 aa.
    
   0.640
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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