STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabRTetR-family trancriptional regulator; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. (213 aa)    
Predicted Functional Partners:
plsB
Glycerol-3-phosphate acyltransferase; Similar to Escherichia coli, and Escherichia coli O6 glycerol-3-phosphate acyltransferase PlsB or b4041 or c5011 SWALL:PLSB_ECOLI (SWALL:P00482) (806 aa) fasta scores: E(): 0, 77.08% id in 803 aa; Belongs to the GPAT/DAPAT family.
  
   
 0.776
ECA4240
Similar to Yersinia pestis putative membrane protein ypo3912 or y0323 SWALL:AAM83914 (EMBL:AJ414159) (135 aa) fasta scores: E(): 3e-29, 63.86% id in 119 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yijd or b3964 or c4927 or z5525 or ecs4895 SWALL:YIJD_ECOLI (SWALL:P27308) (119 aa) fasta scores: E(): 4.3e-29, 65.48% id in 113 aa.
  
    0.758
metJ
Repressor of the methionine regulon; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
   
 0.747
fadR
Fatty acid metabolism regulator; Multifunctional regulator of fatty acid metabolism.
  
  
 0.727
seqA
Putative negative regulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
   
 0.712
rraB
Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.691
yihI
Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.683
ECA2748
Similar to Yersinia pestis hypothetical protein Ypo1261 SWALL:Q8ZGM6 (EMBL:AJ414147) (75 aa) fasta scores: E(): 4.5e-22, 85.52% id in 76 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yejl or stm2227 or sty2465 SWALL:Q8XEL6 (EMBL:AE008799) (75 aa) fasta scores: E(): 1.6e-19, 78.94% id in 76 aa; Belongs to the UPF0352 family.
  
     0.662
dsbB
Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
 
     0.658
nlpI
Lipoprotein; May be involved in cell division.
  
     0.645
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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