STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4246Putative sugar binding transcriptional regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribose operon repressor RbsR or b3753 or c4681 or z5254 or ecs4695 or sf3836 SWALL:RBSR_ECOLI (SWALL:P25551) (329 aa) fasta scores: E(): 1.9e-18, 30.63% id in 333 aa, and to Rhizobium meliloti putative transcriptional regulator protein rb0352 or smb20366 SWALL:Q92WI7 (EMBL:AL603643) (334 aa) fasta scores: E(): 8.1e-42, 43.84% id in 317 aa. (334 aa)    
Predicted Functional Partners:
ECA4248
Similar to Bradyrhizobium japonicum ABC transporter permease protein blr3545 SWALL:BAC48810 (EMBL:AP005948) (293 aa) fasta scores: E(): 1.5e-10, 26.61% id in 278 aa, and to Agrobacterium tumefaciens ABC transporter, membrane spanning protein atu4570 or agr_l_602 SWALL:Q8U784 (EMBL:AE009385) (285 aa) fasta scores: E(): 2e-10, 24.72% id in 275 aa.
 
     0.802
ECA4247
Similar to Agrobacterium tumefaciens ABC transporter, membrane spanning protein atu4571 or agr_l_601 SWALL:Q8U783 (EMBL:AE009385) (288 aa) fasta scores: E(): 3.3e-27, 34.36% id in 259 aa, and to Yersinia pestis putative binding-protein-dependent transport system membrane protein ypo2030 or y2280 SWALL:AAM85839 (EMBL:AJ414151) (278 aa) fasta scores: E(): 4.1e-24, 30.62% id in 271 aa.
 
     0.799
gntR-2
Partial CDS. Similar to the C-terminal regions of Escherichia coli, and Escherichia coli O6 gluconate utilization system Gnt-I transcriptional repressor GntR or b3438 or c4227 SWALL:GNTR_ECOLI (SWALL:P46860) (331 aa) fasta scores: E(): 4.1e-47, 78.36% id in 171 aa, and to Yersinia pestis gluconate utilization system Gnt-I transcriptional repressor gntr or ypo3955 or y3873 SWALL:Q8ZA63 (EMBL:AJ414160) (331 aa) fasta scores: E(): 1.8e-47, 78.94% id in 171 aa.
  
     0.773
ECA3772
Similar to Yersinia pestis LacI-family transcriptional regulatory protein ypo2568 SWALL:Q8ZDJ4 (EMBL:AJ414152) (344 aa) fasta scores: E(): 4.7e-70, 54.46% id in 336 aa, and to Escherichia coli O6 putative conserved protein c0337 SWALL:AAN78825 (EMBL:AE016756) (343 aa) fasta scores: E(): 1.6e-67, 56.45% id in 310 aa.
  
     0.772
scrR
Sucrose operon repressor; Similar to Erwinia amylovora repressor scrR SWALL:Q9F497 (EMBL:AJ250722) (342 aa) fasta scores: E(): 4.7e-86, 65.46% id in 333 aa, and to Klebsiella pneumoniae sucrose operon repressor scrR SWALL:SCRR_KLEPN (SWALL:P37076) (334 aa) fasta scores: E(): 5.5e-88, 65.07% id in 335 aa.
  
     0.771
ECA1966
Putative transcriptional repressor; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri transcriptional repressor CytR or b3934 or c4887 or z5481 or ecs4861 or sf4012 SWALL:CYTR_ECOLI (SWALL:P06964) (341 aa) fasta scores: E(): 2.1e-16, 25.88% id in 340 aa, and to Yersinia pestis LacI-family regulatory protein ypo0846 or y3231 SWALL:Q8ZHP4 (EMBL:AJ414145) (360 aa) fasta scores: E(): 2.3e-80, 56.66% id in 360 aa.
  
     0.768
ECA2487
LacI-family transcriptional regulator; Similar to Haemophilus influenzae galactose operon repressor GalR or GalS or hi0821 SWALL:GALR_HAEIN (SWALL:P31766) (332 aa) fasta scores: E(): 5.7e-09, 31.02% id in 303 aa, and to Staphylococcus xylosus probable catabolite control protein A CcpA SWALL:CCPA_STAXY (SWALL:Q56194) (329 aa) fasta scores: E(): 2.5e-08, 26.36% id in 311 aa.
  
     0.740
ECA4249
ABC transporter periplasmic binding protein; Similar to Escherichia coli, and Escherichia coli O157:H7 maltose-binding periplasmic protein precursor MalE or b4034 or z5632 or ecs5017 SWALL:MALE_ECOLI (SWALL:P02928) (396 aa) fasta scores: E(): 0.00014, 26.87% id in 387 aa, and to Yersinia pestis putative ABC transporter periplasmic binding protein y2281 SWALL:AAM85840 (EMBL:AE013831) (360 aa) fasta scores: E(): 6.8e-13, 26.11% id in 337 aa.
 
     0.629
pdeA
Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
       0.626
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
    
 
 0.592
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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