STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4249ABC transporter periplasmic binding protein; Similar to Escherichia coli, and Escherichia coli O157:H7 maltose-binding periplasmic protein precursor MalE or b4034 or z5632 or ecs5017 SWALL:MALE_ECOLI (SWALL:P02928) (396 aa) fasta scores: E(): 0.00014, 26.87% id in 387 aa, and to Yersinia pestis putative ABC transporter periplasmic binding protein y2281 SWALL:AAM85840 (EMBL:AE013831) (360 aa) fasta scores: E(): 6.8e-13, 26.11% id in 337 aa. (377 aa)    
Predicted Functional Partners:
ECA4248
Similar to Bradyrhizobium japonicum ABC transporter permease protein blr3545 SWALL:BAC48810 (EMBL:AP005948) (293 aa) fasta scores: E(): 1.5e-10, 26.61% id in 278 aa, and to Agrobacterium tumefaciens ABC transporter, membrane spanning protein atu4570 or agr_l_602 SWALL:Q8U784 (EMBL:AE009385) (285 aa) fasta scores: E(): 2e-10, 24.72% id in 275 aa.
 
     0.909
ECA4247
Similar to Agrobacterium tumefaciens ABC transporter, membrane spanning protein atu4571 or agr_l_601 SWALL:Q8U783 (EMBL:AE009385) (288 aa) fasta scores: E(): 3.3e-27, 34.36% id in 259 aa, and to Yersinia pestis putative binding-protein-dependent transport system membrane protein ypo2030 or y2280 SWALL:AAM85839 (EMBL:AJ414151) (278 aa) fasta scores: E(): 4.1e-24, 30.62% id in 271 aa.
 
     0.901
ECA4250
Similar to Escherichia coli putrescine transport ATP-binding protein PotG or b0855 SWALL:POTG_ECOLI (SWALL:P31134) (377 aa) fasta scores: E(): 1.2e-43, 41.97% id in 355 aa, and to Bradyrhizobium japonicum ABC transporter ATP-binding protein bll7196 SWALL:BAC52461 (EMBL:AP005961) (365 aa) fasta scores: E(): 1e-45, 44.02% id in 318 aa, and to Rhizobium meliloti putative ABC transporter, ATP-binding protein ra1191 or sma2207 SWALL:Q92XQ3 (EMBL:AE007304) (361 aa) fasta scores: E(): 1.5e-45, 43.42% id in 350 aa.
 
     0.782
ECA4246
Putative sugar binding transcriptional regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri ribose operon repressor RbsR or b3753 or c4681 or z5254 or ecs4695 or sf3836 SWALL:RBSR_ECOLI (SWALL:P25551) (329 aa) fasta scores: E(): 1.9e-18, 30.63% id in 333 aa, and to Rhizobium meliloti putative transcriptional regulator protein rb0352 or smb20366 SWALL:Q92WI7 (EMBL:AL603643) (334 aa) fasta scores: E(): 8.1e-42, 43.84% id in 317 aa.
 
     0.629
pdeA
Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
       0.483
ECA0366
Similar to Escherichia coli O6 hypothetical protein c3274 SWALL:AAN81723 (EMBL:AE016765) (103 aa) fasta scores: E(): 2.1e-22, 55.34% id in 103 aa.
  
     0.454
ECA2358
Putative aldolase; Similar to Rhizobium loti tagatose-1,6-bisphosphate aldolase mlr3411 SWALL:Q98GB1 (EMBL:AP003001) (302 aa) fasta scores: E(): 2.3e-75, 62.75% id in 298 aa, and to Streptococcus mutans tagatose 1,6-diphosphate aldolase LacD or smu.1493 SWALL:LACD_STRMU (SWALL:P26425) (325 aa) fasta scores: E(): 4.2e-06, 23.19% id in 319 aa.
  
     0.425
ECA3750
Similar to Agrobacterium tumefaciens hypothetical protein atu4562 or agr_l_617 SWALL:Q8U792 (EMBL:AE009384) (840 aa) fasta scores: E(): 4e-114, 38.74% id in 826 aa.
  
     0.418
ECA2234
Similar to Xanthomonas axonopodis hypothetical protein Xac2153 SWALL:Q8PKL8 (EMBL:AE011852) (196 aa) fasta scores: E(): 3.6e-35, 45.69% id in 186 aa, and to Saccharomyces cerevisiae hypothetical 22.0 kDa protein in hxt11-hxt8 intergenic region yjl217w or j0226 or hrc198 SWALL:YJV7_YEAST (SWALL:P40893) (198 aa) fasta scores: E(): 1.2e-33, 45.83% id in 192 aa.
  
     0.411
metL
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase II MetL or MetM or b3940 SWALL:AK2H_ECOLI (SWALL:P00562) (809 aa) fasta scores: E(): 0, 83.12% id in 800 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
       0.411
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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