STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metBSimilar to Escherichia coli cystathionine gamma-synthase MetB or b3939 SWALL:METB_ECOLI (SWALL:P00935) (386 aa) fasta scores: E(): 3.8e-129, 87.01% id in 385 aa. (386 aa)    
Predicted Functional Partners:
metL
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase II MetL or MetM or b3940 SWALL:AK2H_ECOLI (SWALL:P00562) (809 aa) fasta scores: E(): 0, 83.12% id in 800 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.998
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I [includes: aspartokinase I; homoserine dehydrogenase I] thra or thra1 or thra2 or b0002 SWALL:AK1H_ECOLI (SWALL:P00561) (820 aa) fasta scores: E(): 0, 82.41% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.991
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.989
metA
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
 
 
 0.989
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.986
ECA4113
Similar to Streptomyces venezuelae cystathionine beta-synthase cbssV SWALL:Q9EYM7 (EMBL:AF319543) (463 aa) fasta scores: E(): 1.5e-28, 36.81% id in 326 aa, and to Rhizobium fredii Y4xP SWALL:Q8RQB8 (EMBL:AF229441) (336 aa) fasta scores: E(): 1.6e-81, 69.06% id in 333 aa.
 
 0.986
metE-2
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Similar to Pseudomonas putida MetE SWALL:Q9AF89 (EMBL:AF363277) (361 aa) fasta scores: E(): 1.6e-114, 82.94% id in 340 aa, and to Agrobacterium tumefaciens 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase MetE or atu3823 or agr_l_2018 SWALL:Q8U9A5 (EMBL:AE009313) (342 aa) fasta scores: E(): 3.4e-124, 90.29% id in 340 aa.
  
 
 0.985
metF
Similar to Erwinia carotovora 5,10-methylenetetrahydrofolate reductase MetF SWALL:METF_ERWCA (SWALL:P71319) (298 aa) fasta scores: E(): 4.2e-114, 97.65% id in 298 aa, and to Escherichia coli, and Shigella flexneri 5,10-methylenetetrahydrofolate reductase MetF or b3941 or sf4019 SWALL:METF_ECOLI (SWALL:P00394) (296 aa) fasta scores: E(): 2.1e-101, 86.05% id in 294 aa.
  
 0.985
cysK
Cysteine synthase A; Similar to Escherichia coli, and Escherichia coli O157:H7 cysteine synthase A CysK or CysZ or b2414 or z3680 or ecs3286 SWALL:CYSK_ECOLI (SWALL:P11096) (322 aa) fasta scores: E(): 1.4e-100, 89.13% id in 322 aa; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.983
metC
Similar to Escherichia coli cystathionine beta-lyase MetC or b3008 SWALL:METC_ECOLI (SWALL:P06721) (395 aa) fasta scores: E(): 8.3e-124, 73.85% id in 394 aa.
  
 
0.982
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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