Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpFGlycerol uptake facilitator protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 glycerol uptake facilitator protein GlpF or b3927 or c4879 or z5472 or ecs4852 SWALL:GLPF_ECOLI (SWALL:P11244) (281 aa) fasta scores: E(): 4.4e-90, 80.71% id in 280 aa; Belongs to the MIP/aquaporin (TC 1.A.8) family. (279 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
 
 
 0.986
glpQ
Similar to Escherichia coli glycerophosphoryl diester phosphodiesterase, periplasmic precursor GlpQ or b2239 SWALL:GLPQ_ECOLI (SWALL:P09394) (358 aa) fasta scores: E(): 4e-103, 72.7% id in 359 aa.
 
 
 0.943
aplK
Glycerol kinase; Involved in catabolism of D-apiose. Catalyzes phosphorylation of apulose to form apulose 4-phosphate.
 
 
 0.922
glpD
Similar to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD or GlyD or b3426 SWALL:GLPD_ECOLI (SWALL:P13035) (501 aa) fasta scores: E(): 9e-157, 76.59% id in 500 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.868
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.799
glpA
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri anaerobic glycerol-3-phosphate dehydrogenase subunit A GlpA or b2241 or z3499 or ecs3126 or sf2323 SWALL:GLPA_ECOLI (SWALL:P13032) (542 aa) fasta scores: E(): 1.1e-153, 72.34% id in 546 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.791
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 
 0.765
pcp
Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
    
 
 0.708
glpB
Anaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.
 
  
 0.685
ppiB
Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
   0.610
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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