STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aguASimilar to Yersinia pestis hypothetical protein Ypo0939 SWALL:Q8ZHG0 (EMBL:AJ414145) (371 aa) fasta scores: E(): 1.3e-117, 75.47% id in 367 aa, and to Shewanella oneidensis conserved hypothetical protein so0887 SWALL:AAN53963 (EMBL:AE015534) (349 aa) fasta scores: E(): 3.9e-99, 67.33% id in 349 aa. (368 aa)    
Predicted Functional Partners:
ECA4274
Similar to Yersinia pestis putative carbon-nitrogen hydrolase ypo0938 or y3324 SWALL:Q8ZHG1 (EMBL:AJ414145) (294 aa) fasta scores: E(): 2.8e-116, 93.87% id in 294 aa, and to Pseudomonas aeruginosa probable hydratase pa0293 SWALL:Q9I6J8 (EMBL:AE004467) (292 aa) fasta scores: E(): 4.5e-79, 65.05% id in 289 aa.
 
 0.999
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
 
  
 0.989
speC
Similar to Escherichia coli ornithine decarboxylase, constitutive SpeC or b2965 SWALL:DCOR_ECOLI (SWALL:P21169) (711 aa) fasta scores: E(): 0, 71.78% id in 716 aa, and to Yersinia pestis ornithine decarboxylase SpeC or ypo0960 or y3347 SWALL:Q8ZHE0 (EMBL:AJ414145) (720 aa) fasta scores: E(): 0, 73.61% id in 720 aa.
    
 0.679
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
    
 0.613
ECA2132
Conserved hypothetical protein; Similar to Pseudomonas putida carbon-nitrogen hydrolase family protein pp3019 SWALL:AAN68627 (EMBL:AE016785) (247 aa) fasta scores: E(): 1.6e-22, 50.35% id in 141 aa, and to Ralstonia solanacearum hypothetical protein rsc0704 or rs01509 SWALL:Q8Y1I6 (EMBL:AL646060) (249 aa) fasta scores: E(): 2.1e-10, 33.33% id in 135 aa.
  
 
 0.583
speD
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
  
   
 0.575
ECA2346
Similar to Salmonella typhi putative oxidoreductase sty1828 SWALL:Q8Z6F0 (EMBL:AL627271) (285 aa) fasta scores: E(): 1.1e-72, 63.7% id in 281 aa, and to Escherichia coli hypothetical protein yeae yeae or b1781 SWALL:YEAE_ECOLI (SWALL:P76234) (284 aa) fasta scores: E(): 4.1e-72, 63.7% id in 281 aa.
   
    0.525
nadC
Similar to Escherichia coli nicotinate-nucleotide pyrophosphorylase [carboxylating] NadC or b0109 SWALL:NADC_ECOLI (SWALL:P30011) (296 aa) fasta scores: E(): 8.2e-73, 68.94% id in 293 aa; Belongs to the NadC/ModD family.
   
    0.499
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]
   
    0.430
ECA3703
Conserved hypothetical phage-related protein; Similar to Salmonella typhi Eha SWALL:O87649 (EMBL:AF091717) (322 aa) fasta scores: E(): 1.5e-63, 86.9% id in 229 aa, and to Vibrio cholerae Eha protein vc1798 SWALL:Q9KR48 (EMBL:AE004256) (383 aa) fasta scores: E(): 6.4e-25, 40.15% id in 386 aa.
   
    0.413
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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