STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4274Similar to Yersinia pestis putative carbon-nitrogen hydrolase ypo0938 or y3324 SWALL:Q8ZHG1 (EMBL:AJ414145) (294 aa) fasta scores: E(): 2.8e-116, 93.87% id in 294 aa, and to Pseudomonas aeruginosa probable hydratase pa0293 SWALL:Q9I6J8 (EMBL:AE004467) (292 aa) fasta scores: E(): 4.5e-79, 65.05% id in 289 aa. (294 aa)    
Predicted Functional Partners:
aguA
Similar to Yersinia pestis hypothetical protein Ypo0939 SWALL:Q8ZHG0 (EMBL:AJ414145) (371 aa) fasta scores: E(): 1.3e-117, 75.47% id in 367 aa, and to Shewanella oneidensis conserved hypothetical protein so0887 SWALL:AAN53963 (EMBL:AE015534) (349 aa) fasta scores: E(): 3.9e-99, 67.33% id in 349 aa.
 
 0.999
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.930
speC
Similar to Escherichia coli ornithine decarboxylase, constitutive SpeC or b2965 SWALL:DCOR_ECOLI (SWALL:P21169) (711 aa) fasta scores: E(): 0, 71.78% id in 716 aa, and to Yersinia pestis ornithine decarboxylase SpeC or ypo0960 or y3347 SWALL:Q8ZHE0 (EMBL:AJ414145) (720 aa) fasta scores: E(): 0, 73.61% id in 720 aa.
    
 0.911
patA
Probable aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
    
  0.903
ECA2639
Putative hydantoinase; Similar to Bacillus halodurans hydantoinase bh1884 SWALL:Q9KBP1 (EMBL:AP001513) (533 aa) fasta scores: E(): 2.5e-93, 50.09% id in 519 aa, and to Enterococcus faecalis hydantoinase/oxoprolinase ef3275 SWALL:AAO82942 (EMBL:AE016957) (517 aa) fasta scores: E(): 7.4e-90, 48.55% id in 519 aa.
    
  0.509
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
     
 0.475
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
     
 0.474
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
 
   
 0.474
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
   
 
 0.454
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.445
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.