STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4282DnaG primase-like protein; Similar to Photorhabdus luminescens DnaG primase-like DnaG SWALL:AAN64202 (EMBL:AY144117) (925 aa) fasta scores: E(): 1e-213, 73.54% id in 926 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri DNA primase DnaG or DnaP or ParB or b3066 or z4419 or ecs3949 or sf3107 SWALL:PRIM_ECOLI (SWALL:P02923) (581 aa) fasta scores: E(): 1.8e-13, 27.62% id in 438 aa. Also similar to ECA3390, (79.939% id), ECA3400 (84.394% id), ECA3407 (87.010% id), ECA3416 (87.010% id), and to ECA4291 (100.000% id). (972 aa)    
Predicted Functional Partners:
ECA0519
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
 
 0.728
ECA4283
Probable integrase/recombinase; Similar to Photorhabdus luminescens Int SWALL:AAN64203 (EMBL:AY144117) (465 aa) fasta scores: E(): 1.2e-82, 63.42% id in 339 aa, and to Ralstonia solanacearum probable integrase/recombinase protein rsp0090 or rs05531 SWALL:Q8XTL6 (EMBL:AL646076) (347 aa) fasta scores: E(): 9.1e-47, 44.09% id in 322 aa. Also similar to ECA3389, (68.421% id), ECA3399 (66.477% id), ECA3406 (66.765% id), ECA3415 (66.765% id), ECA4292 (100.000% id); Belongs to the 'phage' integrase family.
 
     0.697
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
 0.687
ECA4281
Putative phage regulatory protein; Similar to Vibrio phage CTX RstR SWALL:Q8LTJ3 (EMBL:AF511000) (112 aa) fasta scores: E(): 2.7e-06, 33.63% id in 110 aa, and to Photorhabdus luminescens Orf9 SWALL:AAN64201 (EMBL:AY144117) (130 aa) fasta scores: E(): 1.5e-10, 34.42% id in 122 aa.
 
     0.640
engA
Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
   
  
 0.590
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
  
 0.571
ECA4284
Putative exported protein; No significant database matches.
       0.529
priB
Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
   
 
 0.478
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 
0.475
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
  
 0.471
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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