STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA4292Probable integrase/recombinase; Similar to Photorhabdus luminescens Int SWALL:AAN64203 (EMBL:AY144117) (465 aa) fasta scores: E(): 1.3e-82, 63.42% id in 339 aa, and to Ralstonia solanacearum probable integrase/recombinase protein rsp0090 or rs05531 SWALL:Q8XTL6 (EMBL:AL646076) (347 aa) fasta scores: E(): 9.2e-47, 44.09% id in 322 aa. Also similar to ECA3389, (68.421% id), ECA3399 (66.477% id), ECA3406 (66.765% id), ECA3415 (66.765% id), ECA4283 (100.000% id). (350 aa)    
Predicted Functional Partners:
ECA4291
DnaG primase-like protein; Similar to Photorhabdus luminescens DnaG primase-like DnaG SWALL:AAN64202 (EMBL:AY144117) (925 aa) fasta scores: E(): 1e-213, 73.54% id in 926 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri DNA primase DnaG or DnaP or ParB or b3066 or z4419 or ecs3949 or sf3107 SWALL:PRIM_ECOLI (SWALL:P02923) (581 aa) fasta scores: E(): 1.8e-13, 27.62% id in 438 aa. Also similar to ECA3390, (79.939% id), ECA3400 (84.394% id), ECA3407 (87.010% id), ECA3416 (87.010% id), and to ECA4282 (100.000% id).
 
     0.697
ECA2637
Similar to Bacteriophage P2 integrase Int SWALL:VINT_BPP2 (SWALL:P36932) (337 aa) fasta scores: E(): 1.2e-68, 54.29% id in 326 aa; Belongs to the 'phage' integrase family.
  
   
 0.680
ftsK
Similar to Escherichia coli cell division protein FtsK or b0890 SWALL:FTSK_ECOLI (SWALL:P46889) (1329 aa) fasta scores: E(): 3.8e-163, 53.6% id in 1347 aa.
  
   
 0.553
recR
Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.544
ECA4290
Putative phage regulatory protein; Similar to Vibrio phage CTX RstR SWALL:Q8LTJ3 (EMBL:AF511000) (112 aa) fasta scores: E(): 2.7e-06, 33.63% id in 110 aa, and to Photorhabdus luminescens Orf9 SWALL:AAN64201 (EMBL:AY144117) (130 aa) fasta scores: E(): 1.5e-10, 34.42% id in 122 aa.
       0.428
xerC
Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the t [...]
 
 
 
0.420
tyrA
Similar to Escherichia coli T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA or b2600 SWALL:TYRA_ECOLI (SWALL:P07023) (373 aa) fasta scores: E(): 1.6e-123, 87.13% id in 373 aa.
  
    0.414
ECA4133
Similar to Yersinia pestis hypothetical protein ypo0128 ypo0128 or y3906 SWALL:AAM87448 (EMBL:AJ414141) (233 aa) fasta scores: E(): 7.3e-52, 56.22% id in 233 aa, and to Salmonella typhi putative competence protein sty4286 SWALL:Q8Z222 (EMBL:AL627281) (227 aa) fasta scores: E(): 7.7e-46, 53.21% id in 233 aa.
   
    0.414
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
   
 0.410
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
  0.404
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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