Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tonB-2TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (287 aa)    
Predicted Functional Partners:
ECA4299
Similar to Neisseria meningitidis biopolymer transport ExbB protein ExbB or nma1984 or nmb1729 SWALL:EXBB_NEIMA (SWALL:P57027) (220 aa) fasta scores: E(): 4.3e-20, 40.3% id in 196 aa, and to Pseudomonas aeruginosa ExbB or ExbB1 or pa0198 SWALL:Q9RMT2 (EMBL:AF190125) (239 aa) fasta scores: E(): 2.1e-44, 58.57% id in 239 aa.
 
 
 0.927
ECA4298
Similar to Neisseria meningitidis biopolymer transport ExbD protein ExbD or nma1983 or nmb1728 SWALL:EXBD_NEIMA (SWALL:P95376) (144 aa) fasta scores: E(): 3.9e-13, 38.57% id in 140 aa, and to Pseudomonas aeruginosa ExbD or ExbD1 or pa0199 SWALL:Q9RMT1 (EMBL:AF190125) (133 aa) fasta scores: E(): 1.8e-24, 55.63% id in 133 aa.
 
 
 0.921
foxA
Ferrioxamine B receptor; Similar to Salmonella typhimurium ferrioxamine B receptor precursor fFoxA or stm0364 SWALL:FOXA_SALTY (SWALL:Q56145) (702 aa) fasta scores: E(): 1.8e-207, 74.35% id in 702 aa.
  
 
 0.827
exbD
Biopolymer transport protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri biopolymer transport ExbD protein SWALL:EXBD_ECOLI (SWALL:P18784) (141 aa) fasta scores: E(): 2.1e-36, 68.79% id in 141 aa.
  
 
 0.788
astB
Sulfate ester ABC transporter permease protein; Similar to Pseudomonas putida AtsB SWALL:Q9R9W6 (EMBL:AF126201) (535 aa) fasta scores: E(): 2e-89, 51.46% id in 513 aa, and to Bacillus subtilis putative aliphatic sulfonates transport permease protein SsuC ssuC SWALL:SSUC_BACSU (SWALL:P40401) (276 aa) fasta scores: E(): 2.1e-26, 36.82% id in 239 aa.
  
    0.777
atsC
Sulfate ester ABC transporter ATP-binding protein; Similar to Pseudomonas putida AtsC SWALL:Q9WWU7 (EMBL:AF126201) (287 aa) fasta scores: E(): 3.8e-47, 57.02% id in 242 aa, and to Bacillus subtilis putative aliphatic sulfonates transport ATP-binding protein SsuB SWALL:SSUB_BACSU (SWALL:P97027) (274 aa) fasta scores: E(): 1.1e-35, 45.88% id in 231 aa.
       0.773
exbB
Biopolymer transport protein; Similar to Escherichia coli, and Escherichia coli O157:H7 biopolymer transport ExbB protein ExbB or b3006 or z4359 or ecs3890 SWALL:EXBB_ECOLI (SWALL:P18783) (244 aa) fasta scores: E(): 9.3e-57, 75.2% id in 242 aa.
  
 
 0.766
ECA1271
Similar to Neisseria meningitidis biopolymer transport ExbB protein WALL:EXBB_NEIMC (SWALL:P95375) (220 aa) fasta scores: E(): 1e-23, 38.42% id in 216 aa, and to Xanthomonas campestris biopolymer transport ExbB protein or xcc0009 SWALL:EXBB_XANCP (SWALL:O34260) (253 aa) fasta scores: E(): 1.8e-24, 39.81% id in 216 aa.
 
 
 0.704
lpp
Major outer membrane lipoprotein; A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
    
   0.683
btuB
Vitamin B12 receptor precursor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
 
 
 
 0.682
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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