STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cepACation efflux pump; Cation-efflux transporter that may have a role in detoxification. (300 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
    0.680
dam
DNA adenine methylase; Similar to Escherichia coli, and Escherichia coli O157:H7 DNA adenine methylase Dam or b3387 or z4740 or ecs4229 SWALL:DMA_ECOLI (SWALL:P00475) (278 aa) fasta scores: E(): 2.7e-78, 70% id in 270 aa.
   
  
 0.643
sotB
Sugar efflux transporter B; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
     
 0.638
ECA2629
Phage DNA adenine methylase; Similar to Escherichia coli, and Escherichia coli O157:H7 DNA adenine methylase Dam or b3387 or z4740 or ecs4229 SWALL:DMA_ECOLI (SWALL:P00475) (278 aa) fasta scores: E(): 1e-47, 47.68% id in 281 aa.
   
  
 0.604
copA
Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa.
 
 
 0.597
zntA
Heavy metal-transporting ATPase; Similar to Escherichia coli lead, cadmium, zinc and mercury transporting ATPase ZntA or b3469 SWALL:ATZN_ECOLI (SWALL:P37617) (732 aa) fasta scores: E(): 1.4e-152, 62.53% id in 710 aa, and to Proteus mirabilis putative P-type cation-translocating membrane ATPase PpaA SWALL:O33448 (EMBL:AJ001437) (692 aa) fasta scores: E(): 5.2e-155, 65.26% id in 688 aa.
 
 
 0.513
argD
Acetylornithine/succinyldiaminopimelate aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
  
 0.497
zitB
Zinc transporter; Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
 
 
0.485
pfkA
6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
       0.483
zntB
Zinc transport protein; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
 
  
 0.405
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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